The Impact of Histological Review on Clinical Management of Testicular Cancer

Authors

  • EVA SEGELOV,

    Corresponding author
    1. Urological Cancer Research Unit and Departments of Clinical Oncology and Urology, Royal Prince Alfred Hospital, Camperdown. Australia; Department of Medicine, Roswell Park Cancer Institute, Buffalo, USA
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  • K. M. COX,

    1. Urological Cancer Research Unit and Departments of Clinical Oncology and Urology, Royal Prince Alfred Hospital, Camperdown. Australia; Department of Medicine, Roswell Park Cancer Institute, Buffalo, USA
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  • D. RAGHAVAN,

    1. Urological Cancer Research Unit and Departments of Clinical Oncology and Urology, Royal Prince Alfred Hospital, Camperdown. Australia; Department of Medicine, Roswell Park Cancer Institute, Buffalo, USA
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  • E. McNEIL,

    1. Urological Cancer Research Unit and Departments of Clinical Oncology and Urology, Royal Prince Alfred Hospital, Camperdown. Australia; Department of Medicine, Roswell Park Cancer Institute, Buffalo, USA
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  • LETITIA LANCASTER,

    1. Urological Cancer Research Unit and Departments of Clinical Oncology and Urology, Royal Prince Alfred Hospital, Camperdown. Australia; Department of Medicine, Roswell Park Cancer Institute, Buffalo, USA
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  • J. ROGERS

    1. Urological Cancer Research Unit and Departments of Clinical Oncology and Urology, Royal Prince Alfred Hospital, Camperdown. Australia; Department of Medicine, Roswell Park Cancer Institute, Buffalo, USA
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Eva Segelov, Department of Clinical Oncology, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, NSW 2050, Australia

Abstract

Summary— Accurate histological diagnosis and staging are critically important in determining the optimal management of patients with testicular cancer. We have assessed the importance of histological review of “outside” pathology reports from 87 patients referred to the Urological Cancer Research Unit. In 28 patients (32%), the reviewed pathology report differed from the outside report. In 10 of these patients (11%), the pathology review resulted in a change of treatment or prognosis from that which would have obtained in the absence of such histological review. Pathology review at a major cancer centre with a subspecialist interest in tumour pathology and a large experience in the management of germ cell malignancy is an essential first step in the treatment of testicular cancer.

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