MD, Epidemiologist and Head of Cancer Registry.
The influence of age on treatment choice and survival in 735 patients with renal carcinoma
Article first published online: 21 NOV 2008
British Journal of Urology
Volume 75, Issue 2, pages 143–147, February 1995
How to Cite
Damhuis, R.A.M. and Blom, J.H.M. (1995), The influence of age on treatment choice and survival in 735 patients with renal carcinoma. British Journal of Urology, 75: 143–147. doi: 10.1111/j.1464-410X.1995.tb07301.x
- Issue published online: 21 NOV 2008
- Article first published online: 21 NOV 2008
- Accepted for publication 30 August 1994
- Renal cancer;
Objective To determine whether age is related to treatment choice and survival in patients with renal carcinoma.
Patients and methods In this retrospective study 735 patients with renal carcinoma, diagnosed between 1982 and 1990 in one of the hospitals connected to the Rotterdam Cancer Registry, were evaluated with respect to treatment choice and survival.
Results Nephrectomy was performed less often in elderly patients, both with and without distant metastases. The resection rate for patients aged 70 years and older was 63% against 82% for younger patients (P < 0.001). Crude 5-year survival rates for patients aged 20–59, 60–69 and 70+ were 54, 38 and 22% respectively. For patients with tumours restricted to the kidney (Robson stage 1), corrected survival rates were 80, 70 and 48% respectively. The overall postoperative mortality was 3.8% and was not related to age (P = 0.73).
Conclusion Treatment choice and outcome in patients with renal carcinoma were affected by age. As the proportion of patients aged 70 years and older, now 38%, will inevitably increase in the next decades, more attention is needed with respect to contraindications for surgical treatment in the elderly.