In many men from the PLCO screening trial authors from the USA identified risk factors for BPH. Their findings are interesting; Asian Americans were at the lowest risk of clinical BPH, with alcohol and possibly cigarettes related to a lower risk for the condition.
Three further papers investigate various epidemiological aspects of LUTS. I think that it is important for we urologists to have a sound epidemiological knowledge of this subject, to answer the increasingly educated questions of our patients.
A further paper from Barcelona describes the results of a urodynamic study in patients with bladder calculi. The authors found that bladder stones are not necessarily associated with BOO, and that the results of urodynamic testing are not influenced by their presence.
To identify risk factors for benign prostatic hyperplasia (BPH).
SUBJECTS AND METHODS
Medical history data, including reported urological conditions and treatments, and risk factor data were collected from 34 694 participants in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, a randomized controlled trial designed to evaluate methods for the early detection of cancer.
Asian men had the lowest risks (odds ratio, 95% confidence interval) for nocturia (0.7, 0.5–0.9), physician-diagnosed BPH (0.3, 0.2–0.5) and transurethral prostatectomy (TURP, 0.2, 0.1–0.6), while risks for Whites and Blacks were similar for most measures of BPH. Greater alcohol intake was associated with decreased nocturia (P trend = 0.002), BPH (P trend < 0.001) and TURP (P trend < 0.001). Current tobacco use was associated with decreased nocturia (0.8, 0.7–0.9), BPH (0.7, 0.6–0.8) and TURP (0.6, 0.4–0.8) but dose–response patterns were weak.
Asian-Americans have the lowest risk of clinical BPH. Alcohol and possibly cigarettes are related to a lower risk for BPH.