A perspective on protein profiling of blood


David B. Agus, Louis Warschaw Prostate Cancer Center, Cedars Sinai Medical Center, 8631 3rd Street, Suite 1001E, Los Angeles, CA 90048, USA.
e-mail: david.agus@cshs.org


Protein profiling of blood is going to lead to huge changes in the development of biomarkers and perhaps also in producing targets for the medical treatment of cancer. Experts in this field from Los Angeles have written an outstanding mini-review about this topic.

Renal cancer has been an area of interest to all of those involved in urological oncology, particularly from the point of view of adjuvant medical treatment either to prevent metastatic disease or to treat it. Authors from Los Angeles have produced a review of great interest on this subject.

There are three other reviews on important issues. Authors from Paris have written about microsatellite instability and TCC of the upper urinary tract, and authors from Bristol have written a mini-review about the options available when considering orthotopic bladder reconstruction. Finally, authors from Dublin have written about a significant problem in renal transplantation, delayed graft function.