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Clinical Pediatric Nephrology Edited by Kanwal Kher, Sudesh P. Makker and H. William Schnaper Taylor and Francis , 2006 ; 595 pp; £175 ISBN- 184184-447-0

The second edition of Clinical Pediatric nephrology comprehensively covers all the main kidney, ureter and bladder problems which are likely to be seen by the general paediatrician and paediatric nephrologist. It has been extensively updated from the original edition and clearly emphasizes the clinical implications of a wide range of paediatric renal disorders. The text book is well structured, the 37 concise chapters being assigned to seven discrete sections. It is an ideal textbook for trainee and non-specialist paediatricians, for paediatric nephrologists and urologists and for their trainees.

The first section provides a sound foundation for the sections to follow. There is a clearly illustrated first chapter outlining advances made in the understanding of the structure and development of the kidney, followed by two chapters which explore the mechanisms by which the kidney handles water and electrolytes, and is involved in the maintenance of total body homeostasis. Section 2 reviews the epidemiology of renal disease in childhood and elaborates on the evaluation of a child presenting with renal disease. These chapters are again well and clearly illustrated, particularly for renal imaging techniques. The third section very comprehensively covers the spectrum of renal parenchymal diseases in childhood, with sections on the pathogenesis, differential diagnosis and treatment of the main primary and secondary parenchymal diseases with which children present. There are some illustrative case histories presented in this section, which are carefully discussed. The fourth section concentrates on a review of renal tubular acidosis and the mechanisms underlying the commoner disorders of renal tubular transport. Section 5 elaborates on acute and chronic renal failure in childhood and thoroughly explores the different forms of renal replacement therapy that are currently available. The different forms of dialysis therapy are very clearly and helpfully illustrated. This section is complemented by a concise review of the importance of nutrition in renal disease. The epidemiology and evaluation of childhood hypertension and its management in infancy and childhood are explored in the penultimate section. The final section provides an excellent overview of paediatric renal developmental disorders and syndromes, urological disorders including different forms of obstructive uropathy, voiding problems, renal stone disease and urinary tract infections.

This textbook represents a significant contribution to the available literature in this area, it is clearly written and excellently illustrated, with significant contributions from experts in the field of paediatric nephrology and urology, and should be regarded as an essential text for all general paediatricians, paediatric nephrologists and urologists.