FIG. S1. Cytarabine Inhibits growth and clonogenicity of prostate cancer cell lines. A, growth inhibition of DU-145, PC3 and 22Rv1 cells by cytarabine using a SRB based assay. Cells were treated in 96-well plates for 72 h with AraC and the results of the SRB assay were expressed as the OD570 as the % of the OD570 relative to untreated control wells. The 50% growth inhibition is indicated with a thin horizontal line. B, Clonogenic activity of cytarabine, doxorubicin and cisplatin on DU-145 cells. Cells were plated in 6-well plates and treated with compound at a concentration corresponding to their respective half maximal inhibitory concentration values for growth inhibition on DU-145 cells as determined in sulforhodamine B assays.

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