• 1
    Ojo AO, Wolfe RA, Held PJ, Port FK, Schmouder RL. Delayed graft function: risk factors and implications for renal allograft survival. Transplantation 1997; 63: 96874
  • 2
    Saidi RF, Elias N, Kawai T et al. Outcome of kidney transplantation using expanded criteria donors and donation after cardiac death kidneys: realities and costs. Am J Transplant 2007; 7: 276974
  • 3
    Burns AT, Davies DR, McLaren AJ, Cerundolo L, Morris PJ, Fuggle SV. Apoptosis in ischemia/reperfusion injury of human renal allografts. Transplantation 1998; 66: 8726
  • 4
    Jassem W, Roake J. The molecular and cellular basis of reperfusion injury following organ transplantation. Transplant Rev 1998; 12: 1433
  • 5
    Hosgood SA, Nicholson ML. Hydrogen sulphide ameliorates ischaemia-reperfusion injury in an experimental model of non-heart-beating donor kidney transplantation. Br J Surg 2010; 97: 2029
  • 6
    Burne-Taney MJ, Kofler J, Yokota N, Weisfeldt M, Traystman RJ, Rabb H. Acute renal failure after whole body ischemia is characterized by inflammation and T cell-mediated injury. Am J Physiol Renal Physiol 2003; 285: F8794
  • 7
    De Greef KE, Ysebaert DK, Ghielli M et al. Neutrophils and acute ischemia-reperfusion injury. J Nephrol 1998; 11: 11022
  • 8
    Nankivell BJ, Chapman JR. Chronic allograft nephropathy: current concepts and future directions. Transplantation 2006; 81: 64354
  • 9
    Murphy SP, Porrett PM, Turka LA. Innate immunity in transplant tolerance and rejection. Immunol Rev 2011; 241: 3948
  • 10
    Takashima S, Koukoulis G, Inokawa H, Sevala M, Egan TM. Inhaled nitric oxide reduces ischemia-reperfusion injury in rat lungs from non-heart-beating donors. J Thorac Cardiovasc Surg 2006; 132: 1329
  • 11
    Sato K, Balla J, Otterbein L et al. Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants. J Immunol 2001; 166: 418594
  • 12
    Caumartin Y, Stephen J, Deng JP et al. Carbon monoxide-releasing molecules protect against ischemia-reperfusion injury during kidney transplantation. Kidney Int 2011; 79: 10809
  • 13
    Alabbassi A, Tran KC, Bloch M et al. The effects of molecules CORM-3 and H2S on renal protection during pulsatile perfusion. Am J Transplant 2011; S2: A1614
  • 14
    Lobb I, Mok A, Lan Z, Wang H, Sener A. Supplemental hydrogen sulphide improves renal transplant function and survival following prolonged cold storage. Am J Transplant 2011; S2: A11235
  • 15
    Elrod JW, Calvert JW, Morrison J et al. Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proc Natl Acad Sci USA 2007; 104: 155605
  • 16
    Nicholson CK, Calvert JW. Hydrogen sulfide and ischemia-reperfusion injury. Pharmacol Res 2010; 62: 28997
  • 17
    Cai WJ, Wang MJ, Moore PK, Jin HM, Yao T, Zhu YC. The novel proangiogenic effect of hydrogen sulfide is dependent on Akt phosphorylation. Cardiovasc Res 2007; 76: 2940
  • 18
    Abe K, Kimura H. The possible role of hydrogen sulfide as an endogenous neuromodulator. J Neurosci 1996; 16: 106671
  • 19
    Johansen D, Ytrehus K, Baxter GF. Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury – evidence for a role of K ATP channels. Basic Res Cardiol 2006; 101: 5360
  • 20
    Henderson PW, Singh SP, Belkin D et al. Hydrogen sulfide protects against ischemia-reperfusion injury in an in vitro model of cutaneous tissue transplantation. J Surg Res 2010; 159: 4515
  • 21
    Bos EM, Leuvenink HG, Snijder PM et al. Hydrogen sulfide-induced hypometabolism prevents renal ischemia/reperfusion injury. J Am Soc Nephrol 2009; 20: 19015
  • 22
    Tripatara P, Patel NS, Collino M et al. Generation of endogenous hydrogen sulfide by cystathionine gamma-lyase limits renal ischemia/reperfusion injury and dysfunction. Lab Invest 2008; 88: 103848
  • 23
    Yamamoto T, Tada T, Brodsky SV et al. Intravital videomicroscopy of peritubular capillaries in renal ischemia. Am J Physiol Renal Physiol 2002; 282: F11505
  • 24
    Ott MC, Scott JR, Bihari A et al. Inhalation of carbon monoxide prevents liver injury and inflammation following hind limb ischemia/reperfusion. FASEB J 2005; 19: 1068
  • 25
    Wunder C, Scott JR, Lush CW et al. Heme oxygenase modulates hepatic leukocyte sequestration via changes in sinusoidal tone in systemic inflammation in mice. Microvasc Res 2004; 68: 209
  • 26
    Johns DG, Ao Z, Willette RN, Macphee CH, Douglas SA. Role of p38 MAP kinase in postcapillary venule leukocyte adhesion induced by ischemia/reperfusion injury. Pharmacol Res 2005; 51: 46371
  • 27
    Brock RW, Lawlor DK, Harris KA, Potter RF. Initiation of remote hepatic injury in the rat: interactions between Kupffer cells, tumor necrosis factor-alpha, and microvascular perfusion. Hepatology 1999; 30: 13742
  • 28
    Caradec J, Sirab N, Keumeugni C et al. ‘Desperate house genes’: the dramatic example of hypoxia. Br J Cancer 2010; 102: 103743
  • 29
    Huber AR, Kunkel SL, Todd RF III, Weiss SJ. Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science 1991; 254: 99102
  • 30
    Eldaif SM, Deneve JA, Wang NP et al. Attenuation of renal ischemia-reperfusion injury by postconditioning involves adenosine receptor and protein kinase C activation. Transpl Int 2010; 23: 21726
  • 31
    Tripatara P, Patel NS, Brancaleone V et al. Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study. Eur J Pharmacol 2009; 606: 2059
  • 32
    Cassis P, Azzollini N, Solini S et al. Both darbepoetin alfa and carbamylated erythropoietin prevent kidney graft dysfunction due to ischemia/reperfusion in rats. Transplantation 2011; 92: 2719
  • 33
    Tucci S Jr, Borelli-Bovo TJ, Cologna AJ, Tiraboschi RB, Martins AC, Roselino JE. Calcium channel blocker and renal mitochondrial function in warm renal ischemia. Int Braz J Urol 2005; 31: 3849
  • 34
    Francis RC, Vaporidi K, Bloch KD, Ichinose F, Zapol WM. Protective and detrimental effects of sodium sulfide and hydrogen sulfide in murine ventilator-induced lung injury. Anesthesiology 2011; 115: 101221
  • 35
    Yates PJ, Hosgood SA, Nicholson ML. A biphasic response to nitric oxide donation in an ex vivo model of donation after cardiac death renal transplantation. J Surg Res 2012; 175: 31621
  • 36
    Patschan D, Patschan S, Müller GA. Inflammation and microvasculopathy in renal ischemia reperfusion injury. J Transplant 2012; 2012: 764154
  • 37
    Zhao W, Zhang J, Lu Y, Wang R. The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener. EMBO J 2001; 20: 600816
  • 38
    Cao C, Lee-Kwon W, Silldorff EP, Pallone TL. KATP channel conductance of descending vasa recta pericytes. Am J Physiol Renal Physiol 2005; 289: F123545
  • 39
    Beltowski J. Hypoxia in the renal medulla: implications for hydrogen sulfide signaling. J Pharmacol Exp Ther 2010; 334: 35863
  • 40
    Daemen MA, van 't Veer C, Denecker G et al. Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest 1999; 104: 5419
  • 41
    Mkaddem SB, Bens M, Vandewalle A. Differential activation of Toll-like receptor-mediated apoptosis induced by hypoxia. Oncotarget 2010; 1: 74150
  • 42
    Wu H, Chen G, Wyburn KR et al. TLR4 activation mediates kidney ischemia/reperfusion injury. J Clin Invest 2007; 117: 284759
  • 43
    Donnahoo KK, Shames BD, Harken AH, Meldrum DR. Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury. J Urol 1999; 162: 196203
  • 44
    Jang HR, Ko GJ, Wasowska BA, Rabb H. The interaction between ischemia-reperfusion and immune responses in the kidney. J Mol Med (Berl) 2009; 87: 85964
  • 45
    Donnahoo KK, Meng X, Ayala A, Cain MP, Harken AH, Meldrum DR. Early kidney TNF-alpha expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion. Am J Physiol 1999; 277: R9229
  • 46
    Mariggio MA, Pettini F, Fumarulo R. Sulfide influence on polymorphonuclear functions: a possible role for Ca2+ involvement. Immunopharmacol Immunotoxicol 1997; 19: 393404
  • 47
    Yusof M, Kamada K, Kalogeris T, Gaskin FS, Korthuis RJ. Hydrogen sulfide triggers late-phase preconditioning in postischemic small intestine by an NO- and p38 MAPK-dependent mechanism. Am J Physiol Heart Circ Physiol 2009; 296: H86876
  • 48
    Zanardo RC, Brancaleone V, Distrutti E, Fiorucci S, Cirino G, Wallace JL. Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation. FASEB J 2006; 20: 211820
  • 49
    Linfert D, Chowdhry T, Rabb H. Lymphocytes and ischemia-reperfusion injury. Transplant Rev (Orlando) 2009; 23: 110
  • 50
    Ko GJ, Linfert D, Jang HR et al. Transcriptional analysis of infiltrating T cells in kidney ischemia-reperfusion injury reveals a pathophysiological role for CCR5. Am J Physiol Renal Physiol 2012; 302: F76273
  • 51
    Serrick C, La FS, Giaid A, Shennib H. Cytokine interleukin-2, tumor necrosis factor-alpha, and interferon-gamma release after ischemia/reperfusion injury in a novel lung autograft animal model. Am J Respir Crit Care Med 1995; 152: 27782
  • 52
    Vaghasiya JD, Sheth NR, Bhalodia YS, Jivani NP. Exaggerated liver injury induced by renal ischemia reperfusion in diabetes: effect of exenatide. Saudi J Gastroenterol 2010; 16: 17480
  • 53
    Golab F, Kadkhodaee M, Zahmatkesh M et al. Ischemic and non-ischemic acute kidney injury cause hepatic damage. Kidney Int 2009; 75: 78392
  • 54
    Hirata K, Ikeda S, Honma T et al. Sepsis and cholestasis: basic findings in the sinusoid and bile canaliculus. J Hepatobiliary Pancreat Surg 2001; 8: 206
  • 55
    Sivarajah A, Collino M, Yasin M et al. Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R. Shock 2009; 31: 26774
  • 56
    Bhatia M, Wong FL, Fu D, Lau HY, Moochhala SM, Moore PK. Role of hydrogen sulfide in acute pancreatitis and associated lung injury. FASEB J 2005; 19: 6235
  • 57
    Li L, Bhatia M, Zhu YZ et al. Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse. FASEB J 2005; 19: 11968
  • 58
    Dal-Secco D, Cunha TM, Freitas A et al. Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: role of ATP-sensitive potassium channels. J Immunol 2008; 181: 428798
  • 59
    Hegde A, Bhatia M. Hydrogen sulfide in inflammation: friend or foe? Inflamm Allergy Drug Targets 2011; 10: 11822