• 1
    Blom JHM, van Poppel H, Maréchal JM et al. Radical nephrectomy with and without lymph-node dissection: final results of European Organization for Research and Treatment of Cancer (EORTC) randomized phase 3 trial 30881. Eur Urol 2009; 55: 2834
  • 2
    Joslyn SA, Sirintrapun SJ, Konety BR. Impact of lymphadenectomy and nodal burden in renal cell carcinoma: retrospective analysis of the National Surveillance, Epidemiology, and End Results database. Urology 2005; 65: 675680
  • 3
    Trinh Q-D, Schmitges J, Bianchi M et al. Node-positive renal cell carcinoma in the absence of distant metastases: predictors of cancer-specific mortality in a population-based cohort. BJU Int 2011; 110: E2127
  • 4
    Pantuck AJ, Zisman A, Dorey F et al. Renal cell carcinoma with retroperitoneal lymph nodes: role of lymph node dissection. J Urol 2003; 169: 20762083
  • 5
    Whitson JM, Harris CR, Reese AC et al. Lymphadenectomy improves survival of patients with renal cell carcinoma and nodal metastases. J Urol 2011; 185: 16151620
  • 6
    Schafer J. Multiple imputation: a primer. Stat Methods Med Res 1999; 8: 315
  • 7
    Horton N, Lipsitz S. Multiple imputation in practice: comparison of software packages for regression models with missing variables. Am Stat Assoc 2001; 55: 244258
  • 8
    Jeldres C, Sun M, Liberman D et al. Can renal mass biopsy assessment of tumor grade be safely substituted for by a predictive model? J Urol 2009; 182: 25852589
  • 9
    Chen S, Bilchik A. More extensive nodal dissection improves survival for stages I to III of colon cancer. Ann Surg 2006; 244: 602610
  • 10
    Le Voyer T, Sigurdson E, Hanlon AL et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol 2003; 21: 29122919
  • 11
    Shirotake S, Kikuchi E, Matsumoto K et al. Role of pelvic lymph node dissection in lymph node-negative patients with invasive bladder cancer. Jpn J Clin Oncol 2010; 40: 247251
  • 12
    Minervini A, Lilas L, Morelli G et al. Regional lymph node dissection in the treatment of renal cell carcinoma: is it useful in patients with no suspected adenopathy before or during surgery? BJU Int 2001; 88: 169172
  • 13
    Trinh Q-D, Saad F, Lattouf J-B. The current management of small renal masses. Curr Opin Support Palliat Care 2009; 3: 180185
  • 14
    Pizzocaro G, Piva L, Salvioni R. Lymph node dissection in radical nephrectomy for renal cell carcinoma: is it necessary? Eur Urol 1983; 9: 1012
  • 15
    Schafhauser W, Ebert A, Brod J et al. Lymph node involvement in renal cell carcinoma and survival chance by systematic lymphadenectomy. Anticancer Res 1999; 19: 15731578
  • 16
    Canfield SE, Kamat AM, Sánchez-Ortiz RF et al. Renal cell carcinoma with nodal metastases in the absence of distant metastatic disease (clinical stage TxN1-2M0): the impact of aggressive surgical resection on patient outcome. J Urol 2006; 175: 864869
  • 17
    Lane BR, Babineau D, Kattan MW et al. A preoperative prognostic nomogram for solid enhancing renal tumors 7 cm or less amenable to partial nephrectomy. J Urol 2007; 178: 429434
  • 18
    National Comprehensive Cancer Network. Kidney cancer. NCCN Clinical Practice Guidelines in Oncology, 2011. Available at: Accessed 20 July 2012
  • 19
    Ljungberg B, Cowan NC, Hanbury DC et al. EAU guidelines on renal cell carcinoma: the 2010 update. Eur Urol 2010; 58: 398406