• 1
    Irwin DE, Milsom I, Kopp Z, Abrams P, Artibani W, Herschorn S. Prevalence, severity, and symptom bother of lower urinary tract symptoms among men in the EPIC study: impact of overactive bladder. Eur Urol 2009; 56: 1420
  • 2
    Glasser DB, Carson C 3rd, Kang JH, Laumann EO. Prevalence of storage and voiding symptoms among men aged 40 years and older in a US population-based study: results from the Male Attitudes Regarding Sexual Health study. Int J Clin Pract 2007; 61: 12941300
  • 3
    Amaro JL, Balasteghin KT, Padovani CR, Montenegro R. Structural alterations of the bladder induced by detrusor instability. Experimental study in rabbits. Int Braz J Urol 2005; 31: 579585
  • 4
    Austin JC, Chacko SK, DiSanto M, Canning DA, Zderic SA. A male murine model of partial bladder outlet obstruction reveals changes in detrusor morphology, contractility and Myosin isoform expression. J Urol 2004; 172: 15241528
  • 5
    Grases F, García-Ferragut L, Costa-Bauzá A. Study of the early stages of renal stone formation: experimental model using urothelium of pig urinary bladder. Urol Res 1996; 24: 305311
  • 6
    Schröder A, Chichester P, Kogan BA et al. Effect of chronic bladder outlet obstruction on blood flow of the rabbit bladder. J Urol 2001; 165: 640646
  • 7
    Harrison SC, Ferguson DR, Doyle PT. Effect of bladder outflow obstruction on the innervation of the rabbit urinary bladder. Br J Urol 1990; 66: 372379
  • 8
    Kato K, Monson FC, Longhurst PA, Wein AJ, Haugaard N, Levin RM. The functional effects of long-term outlet obstruction on the rabbit urinary bladder. J Urol 1990; 143: 600606
  • 9
    Levin RM, Leggett RE, Whitbeck C et al. Kohki tea protects the rabbit bladder from ischemia/reperfusion-induced contractile dysfunction. Urol Int 2008; 80: 425430
  • 10
    Levin RM, Haugaard N, O'Connor L et al. Obstructive response of human bladder to BPH vs., rabbit bladder response to partial outlet obstruction: a direct comparison. Neurourol Urodyn 2000; 19: 609629
  • 11
    Buttyan R, Chen MW, Levin RM. Animal models of bladder outlet obstruction and molecular insights into the basis for the development of bladder dysfunction. Eur Urol 1997; 32 (Suppl. 1): 3239
  • 12
    Rule AD, Lieber MM, Jacobsen SJ. Is benign prostatic hyperplasia a risk factor for chronic renal failure? J Urol 2005; 173: 691696
  • 13
    Comiter CV, Sullivan MP, Schacterle RS, Cohen LH, Valla SV. Urodynamic risk factors for renal dysfunction in men with obstructive and nonobstructive voiding dysfunction. J Urol 1997; 158: 181185
  • 14
    Rule AD, Jacobson DJ, Roberts RO et al. The association between benign prostatic hyperplasia and chronic kidney disease in community-dwelling men. Kidney Int 2005; 67: 23762382
  • 15
    Mauroy B. Bladder consequences of prostatic obstruction. Eur Urol 1997; 32 (Suppl. 1): 38
  • 16
    Lin VK, McConnell JD. Molecular aspects of bladder outlet obstruction. Adv Exp Med Biol 1995; 385: 6574
  • 17
    Anumanthan G, Tanaka ST, Adams CM et al. Bladder stromal loss of transforming growth factor receptor II decreases fibrosis after bladder obstruction. J Urol 2009; 182 (Suppl.): 17751780
  • 18
    Peters CA, Freeman MR, Fernandez CA, Shepard J, Wiederschain DG, Moses MA. Dysregulated proteolytic balance as the basis of excess extracellular matrix in fibrotic disease. Am J Physiol 1997; 272: R19601965
  • 19
    Nagase H, Woessner JF Jr. Matrix metalloproteinases. J Biol Chem 1999; 274: 2149121494
  • 20
    Kleiner DE Jr, Stetler-Stevenson WG. Structural biochemistry and activation of matrix metalloproteases. Curr Opin Cell Biol 1993; 5: 891897
  • 21
    Backhaus BO, Kaefer M, Haberstroh KM et al. Alterations in the molecular determinants of bladder compliance at hydrostatic pressures less than 40 cm. H2O. J Urol 2002; 168: 26002604
  • 22
    Stanton MC, Austin JC, Delaney DP et al. Partial bladder outlet obstruction selectively abolishes protein kinase C induced contraction of rabbit detrusor smooth muscle. J Urol 2006; 176: 27162721
  • 23
    Zhang EY, Stein R, Chang S et al. Smooth muscle hypertrophy following partial bladder outlet obstruction is associated with overexpression of non-muscle caldesmon. Am J Pathol 2004; 164: 601612
  • 24
    Levin RM, Das AK, Haugaard N et al. Beneficial effects of Tadenan therapy after two weeks of partial obstruction in the rabbit. Neurourol Urodyn 1997; 16: 583599
  • 25
    MacDougall JR, Matrisian L. Contributions of tumour and stromal matrix metalloproteinases to tumour progression, invasion and metastasis. Cancer Metastasis Rev 1995; 14: 351362
  • 26
    Greene J, Wang M, Liu YE, Raymond LA, Rosen C, Shi YE. Molecular cloning and characterisation of human tissue inhibitor of metalloproteinase-4. J Biol Chem 1996; 271: 3037530380