Short-term effects of severe dietary carbohydrate-restriction advice in Type 2 diabetes—a randomized controlled trial
Version of Record online: 1 SEP 2005
Volume 23, Issue 1, pages 15–20, January 2006
How to Cite
Daly, M. E., Paisey, R., Paisey, R., Millward, B. A., Eccles, C., Williams, K., Hammersley, S., MacLeod, K. M. and Gale, T. J. (2006), Short-term effects of severe dietary carbohydrate-restriction advice in Type 2 diabetes—a randomized controlled trial. Diabetic Medicine, 23: 15–20. doi: 10.1111/j.1464-5491.2005.01760.x
- Issue online: 1 SEP 2005
- Version of Record online: 1 SEP 2005
- Accepted 16 March 2005
- dietary carbohydrate;
- weight loss;
- Type 2 diabetes;
Objective This study sought to examine the effects of a 3-month programme of dietary advice to restrict carbohydrate intake compared with reduced-portion, low-fat advice in obese subjects with poorly controlled Type 2 diabetes.
Research design and methods One hundred and two patients with Type 2 diabetes were recruited across three centres and randomly allocated to receive group education and individual dietary advice. Weight, glycaemic control, lipids and blood pressure were assessed at baseline and 3 months. Dietary quality was assessed at the end of study.
Results Weight loss was greater in the low-carbohydrate (LC) group (−3.55 ± 0.63, mean ± sem) vs. −0.92 ± 0.40 kg, P = 0.001) and cholesterol : high-density lipoprotein (HDL) ratio improved (−0.48 ± 0.11 vs. −0.10 ± 0.10, P = 0.01). However, relative saturated fat intake was greater (13.9 ± 0.71 vs. 11.0 ± 0.47% of dietary intake, P < 0.001), although absolute intakes were moderate.
Conclusions Carbohydrate restriction was an effective method of achieving short-term weight loss compared with standard advice, but this was at the expense of an increase in relative saturated fat intake.