SEARCH

SEARCH BY CITATION

References

  • 1
    Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001; 414: 799806.
  • 2
    Zhang Y, Scarpace PJ. The role of leptin in leptin resistance and obesity. Physiol Behav 2006; 88: 249256.
  • 3
    Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR et al . Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996; 334: 292295.
  • 4
    Donahue RP, Prineas RJ, Donahue RD, Zimmet P, Bean JA, De Court M et al . Is fasting leptin associated with insulin resistance among nondiabetic individuals? The Miami Community Health Study. Diabetes Care 1999; 22: 10921096.
  • 5
    Wauters M, Considine RV, Yudkin JS, Peiffer F, De Leeuw I, Van Gaal LF. Leptin levels in Type 2 diabetes: associations with measures of insulin resistance and insulin secretion. Horm Metab Res 2003; 35: 9296.
  • 6
    Fu Y, Luo N, Klein RL, Garvey WT. Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. J Lipid Res 2005; 46: 13691379.
  • 7
    Thamer C, Haap M, Heller E, Joel L, Braun S, Tschritter O et al . Beta cell function, insulin resistance and plasma adiponectin concentrations are predictors for the change of postprandial glucose in non-diabetic subjects at risk for Type 2 diabetes. Horm Metab Res 2006; 38: 178182.
  • 8
    Koebnick C, Roberts CK, Shaibi GQ, Kelly LA, Lane CL, Toledo-Corral C et al . Adiponectin and leptin are independently associated with insulin sensitivity but not insulin secretion or beta-cell function in overweight Hispanic adolescents. Horm Metab Res 2008; in press. Epub 8 June 2008, PMID 18563679.
  • 9
    Bluher S, Mantzoros CS. Leptin in reproduction. Curr Opin Endocrinol Diabetes Obes 2007; 14: 458464.
  • 10
    Maqsood AR, Trueman JA, Whatmore AJ, Westwood M, Price DA, Hall CM et al . The relationship between nocturnal urinary leptin and gonadotrophins as children progress towards puberty. Horm Res 2007; 68: 225230.
  • 11
    Jansson PA, Eliasson B, Lindmark S, Eriksson JW. Endocrine abnormalities in healthy first-degree relatives of Type 2 diabetes patients—potential role of steroid hormones and leptin in the development of insulin resistance. Eur J Clin Invest 2002; 32: 172178.
  • 12
    Nyholm B, Fisker S, Lund S, Moller N, Schmitz O. Increased circulating leptin concentrations in insulin-resistant first-degree relatives of patients with non-insulin-dependent diabetes mellitus: relationship to body composition and insulin sensitivity but not to family history of non-insulin-dependent diabetes mellitus. Eur J Endocrinol 1997; 136: 173179.
  • 13
    Vauhkonen I, Niskanen L, Haffner S, Kainulainen S, Uusitupa M, Laakso M. Insulin resistant phenotype is associated with high serum leptin levels in offspring of patients with non-insulin-dependent diabetes mellitus. Eur J Endocrinol 1998; 139: 598604.
  • 14
    Behre CJ, Brohall G, Hulthe J, Fagerberg B. Serum adiponectin in a population sample of 64-year-old women in relation to glucose tolerance, family history of diabetes, autoimmunity, insulin sensitivity, C-peptide, and inflammation. Metabolism 2006; 55: 188194.
  • 15
    Civitarese AE, Jenkinson CP, Richardson D, Bajaj M, Cusi K, Kashyap S et al . Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes. Diabetologia 2004; 47: 816820.
  • 16
    Furuhashi M, Ura N, Higashiura K, Miyazaki Y, Murakami H, Hyakukoku M et al . Low adiponectin level in young normotensive men with a family history of essential hypertension. Hypertens Res 2005; 28: 141146.
  • 17
    Kowalska I, Straczkowski M, Nikolajuk A, Krukowska A, Kinalska I, Gorska M. Plasma adiponectin concentration and tumor necrosis factor-alpha system activity in lean non-diabetic offspring of Type 2 diabetic subjects. Eur J Endocrinol 2006; 154: 319324.
  • 18
    Pellme F, Smith U, Funahashi T, Matsuzawa Y, Brekke H, Wiklund O et al . Circulating adiponectin levels are reduced in nonobese but insulin-resistant first-degree relatives of Type 2 diabetic patients. Diabetes 2003; 52: 11821186.
  • 19
    Mitchell BD, Valdez R, Hazuda HP, Haffner SM, Monterrosa A, Stern MP. Differences in the prevalence of diabetes and impaired glucose tolerance according to maternal or paternal history of diabetes. Diabetes Care 1993; 16: 12621267.
  • 20
    Goran MI, Bergman RN, Avila Q, Watkins M, Ball GD, Shaibi GQ et al . Impaired glucose tolerance and reduced beta-cell function in overweight Latino children with a positive family history for Type 2 diabetes. J Clin Endocrinol Metab 2004; 89: 207212.
  • 21
    Bergman RN, Phillips LS, Cobelli C. Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 1981; 68: 14561467.
  • 22
    Boston RC, Stefanovski D, Moate PJ, Sumner AE, Watanabe RM, Bergman RN. MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diabetes Technol Ther 2003; 5: 10031015.
  • 23
    Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C et al . Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study. Diabetes 2008; 57: 11471150.
  • 24
    Imagawa K, Numata Y, Katsuura G, Sakaguchi I, Morita A, Kikuoka S et al . Structure–function studies of human leptin. J Biol Chem 1998; 273: 3524535249.
  • 25
    Ren W, Zhang SH, Wu J, Ni YX. Polymorphism of the leptin gene promoter in pedigrees of Type 2 diabetes mellitus in Chongqing, China. Chin Med J (Engl) 2004; 117: 558561.
  • 26
    Hoffstedt J, Eriksson P, Mottagui-Tabar S, Arner P. A polymorphism in the leptin promoter region (−2548 G/A) influences gene expression and adipose tissue secretion of leptin. Horm Metab Res 2002; 34: 355359.
  • 27
    Hager J, Clement K, Francke S, Dina C, Raison J, Lahlou N et al . A polymorphism in the 5′ untranslated region of the human ob gene is associated with low leptin levels. Int J Obes Relat Metab Disord 1998; 22: 200205.
  • 28
    Lakka TA, Rankinen T, Weisnagel SJ, Chagnon YC, Lakka HM, Ukkola O et al . Leptin and leptin receptor gene polymorphisms and changes in glucose homeostasis in response to regular exercise in nondiabetic individuals: the HERITAGE family study. Diabetes 2004; 53: 16031608.
  • 29
    Lucantoni R, Ponti E, Berselli ME, Savia G, Minocci A, Calo G et al . The A19G polymorphism in the 5′ untranslated region of the human obese gene does not affect leptin levels in severely obese patients. J Clin Endocrinol Metab 2000; 85: 35893591.
  • 30
    Mammes O, Betoulle D, Aubert R, Giraud V, Tuzet S, Petiet A et al . Novel polymorphisms in the 5′ region of the LEP gene: association with leptin levels and response to low-calorie diet in human obesity. Diabetes 1998; 47: 487489.
  • 31
    Stoger R. The thrifty epigenotype: an acquired and heritable predisposition for obesity and diabetes? Bioessays 2008; 30: 156166.
  • 32
    Horlick MB, Rosenbaum M, Nicolson M, Levine LS, Fedun B, Wang J et al . Effect of puberty on the relationship between circulating leptin and body composition. J Clin Endocrinol Metab 2000; 85: 25092518.
  • 33
    Kelly LA, Lane CJ, Weigensberg MJ, Koebnick C, Roberts CK, Davis JN et al . Parental history and risk of Type 2 diabetes in overweight Latino adolescents: a longitudinal analysis. Diabetes Care 2007; 30: 27002705.