• chronic disease;
  • diabetes;
  • hypertension;
  • internet;
  • obesity


Aims  The rapidly increasing prevalence of chronic diseases is an important challenge to healthcare systems worldwide. To improve the quality and efficiency of chronic disease care, we investigated the effectiveness and applicability of the Ubiquitous Chronic Disease Care (UCDC) system using cellular phones and the internet for overweight patients with both Type 2 diabetes and hypertension.

Methods  We conducted a randomized, controlled clinical trial over 3 months that included 123 patients at a university hospital and a community public health centre.

Results  After 12 weeks, there were significant improvements in HbA1c in the intervention group (7.6 ± 0.9% to 7.1 ± 0.8%, P < 0.001) compared with the control group (7.4 ± 0.9% to 7.6 ± 1.0%, P = 0.03). Furthermore, we observed a significant reduction in systolic and diastolic blood pressure, as well as improvements in total cholesterol, low-density lipoprotein-cholesterol and triglyceride levels in the intervention group. Furthermore, there was a significant increase in adiponectin levels in the intervention group compared with the control group, although high-sensitivity C-reactive protein and interleukin-6 levels did not change in either group.

Conclusions  The novel UCDC system presented in this paper improved multiple metabolic parameters simultaneously in overweight patients with both Type 2 diabetes and hypertension.