Effect of carbohydrate counting and medical nutritional therapy on glycaemic control in Type 1 diabetic subjects: a pilot study
Article first published online: 12 JAN 2010
© 2010 The Authors. Journal compilation © 2010 Diabetes UK
Volume 27, Issue 4, pages 477–479, April 2010
How to Cite
Scavone, G., Manto, A., Pitocco, D., Gagliardi, L., Caputo, S., Mancini, L., Zaccardi, F. and Ghirlanda, G. (2010), Effect of carbohydrate counting and medical nutritional therapy on glycaemic control in Type 1 diabetic subjects: a pilot study. Diabetic Medicine, 27: 477–479. doi: 10.1111/j.1464-5491.2010.02963.x
- Issue published online: 7 APR 2010
- Article first published online: 12 JAN 2010
- Accepted 5 January 2009
- carbohydrate counting;
- insulin requirement;
- medical nutritional therapy;
- metabolic control;
- Type 1 diabetes
Diabet. Med. 27, 477–479 (2010)
Aims The effect of a balanced, carbohydrate-counting diet on glycaemic control in Type 1diabetic subjects is unclear. Our aim was to determine its effect in a small, pilot trial.
Methods We randomized 256 Type 1 diabetic subjects to a Nutritional Education Programme (group A) or not (group B). Weight, body mass index, glycated haemogobin (HbA1c), lipid profile, urate, creatinine, microalbuminuria and daily insulin requirements were measured at baseline and at the end of the study (9 months). During the study, the number of hypoglycaemic events (bood glucose < 3.9 mmol/l) was also measured.
Results Compared with group B, group A showed: (i) a reduction in HbA1c (group A: 7.8 ± 1.3–7.4 ± 0.9%; group B: 7.5 ± 0.8–7.5 ± 1.1%; P < 0.01); (ii) less hypoglycaemic events (4% vs. 7%; P < 0.05); (iii) a reduction in dose of rapid insulin analogues (23.5 ± 10.9 vs. 27.7 ± 17.1 IU/24 h; P = 0.03). No other between-group changes were observed.
Conclusions This study shows the importance of medical nutritional therapy on glycaemic control in Type 1 diabetic subjects.