Medetomidine and dexmedetomidine: a review of cardiovascular effects and antinociceptive properties in the dog
Article first published online: 6 MAY 2005
Veterinary Anaesthesia and Analgesia
Volume 32, Issue 3, pages 117–127, May 2005
How to Cite
Murrell, J. C. and Hellebrekers, L. J. (2005), Medetomidine and dexmedetomidine: a review of cardiovascular effects and antinociceptive properties in the dog. Veterinary Anaesthesia and Analgesia, 32: 117–127. doi: 10.1111/j.1467-2995.2005.00233.x
- Issue published online: 6 MAY 2005
- Article first published online: 6 MAY 2005
- Received 22 November 2003; accepted 16 December 2004.
Alpha2-adrenoreceptor agonists (α2-agonists) are commonly used in small animal anaesthesia for their potent sedative and analgesic properties, although concerns about their cardiovascular effects have prevented their full adoption into veterinary practice. Research into alpha2 adrenoreceptor agonists and their clinical use is extensive, therefore this review focuses on the use of dexmedetomidine and medetomidine in dogs. Emphasis is given to the cardiovascular effects and antinociceptive action of these agents.