ABSTRACT For 21 consecutive days, 186 male and female college students recalled the most stressful event of the day, recorded how the event was appraised, and indicated the coping methods they employed as well as their perceived effectiveness and the sequence in which they were used. Gender differences in seven coping strategies were examined in terms of frequency of use, extent of use, relative use, and the frequency with which each method was used first in the coping sequence. The gender differences that emerged were consistent with a socialization hypothesis that predicts more problem-focused coping in men and more use of support seeking and emotion-focused coping in women. Both men and women rated problem-focused coping responses as more generally effective than seeking social support, and the latter as more effective than emotion-focused coping responses. Additionally, we explored the roles of stressor type and of threat, challenge, and control appraisals in the observed gender differences.