Abstract This study investigated the relations of the proposed sixth factor of personality, Honesty-Humility, with the dimensions of the classic English lexical Big Five and the closely related Five-Factor Model (FFM). Results showed that although Honesty-Humility was largely unrelated to markers of the Big Five factors, it was substantially correlated with the FFM Agreeableness domain. This relation was largely due to the Straightforwardness and Modesty facets of FFM Agreeableness, which were only weakly correlated with the Big Five version of Agreeableness. A realignment of FFM facets to produce separate Honesty-Humility and Agreeableness factors provided better prediction of personality variables that involve deceit without hostility, such as Social Adroitness and Self-Monitoring. Results indicate the importance of assessing Honesty-Humility as a separate factor.