A Genome-Wide Scan for Eysenckian Personality Dimensions in Adolescent Twin Sibships: Psychoticism, Extraversion, Neuroticism, and Lie


  • These studies have been supported from multiple sources: National Health and Medical Research Council (901061, 950998, 241944), Queensland Cancer Fund, Australian Research Council (A79600334, A79801419, A79906588, DP0212016), Human Frontiers Science Program (RG0154/1998-B), Beyond Blue, and The Eysenck Memorial Fund. Finally, we warmly thank the twins and their family members for their continued support, generosity of time, and for their interest in this research.

concerning this article may be sent to Nathan A Gillespie, Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond VA 23298-0126; E-mail: ngillespie@vcu.edu.


ABSTRACT We report the first genome-wide scan of adolescent personality. We conducted a genome-wide scan to detect linkage for measures of adolescent Psychoticism, Extraversion, Neuroticism, and Lie from the Junior Eysenck Personality Questionnaire. Data are based on 1,280 genotyped Australian adolescent twins and their siblings. The highest linkage peaks were found on chromosomes 16 and 19 for Neuroticism, on chromosomes 1, 7, 10, 13 m, and 18 for Psychoticism, and on chromosomes 2 and 3 for Extraversion.