Core temperature: a forgotten variable in energy expenditure and obesity?
Version of Record online: 29 OCT 2012
© 2012 The Author. obesity reviews © 2012 International Association for the Study of Obesity
Special Issue: Body Composition, Inflammation and Thermogenesis in Pathways to Obesity and the Metabolic Syndrome. 6th Fribourg Obesity Research Conference (FORC)-2011
Volume 13, Issue Supplement S2, pages 97–104, December 2012
How to Cite
Landsberg, L. (2012), Core temperature: a forgotten variable in energy expenditure and obesity?. Obesity Reviews, 13: 97–104. doi: 10.1111/j.1467-789X.2012.01040.x
- Issue online: 29 OCT 2012
- Version of Record online: 29 OCT 2012
- Manuscript Accepted: 4 SEP 2012
- Manuscript Received: 3 SEP 2012
- Feinberg Foundation
- Core temperature;
- metabolic rate;
A substantial proportion of energy expenditure is utilized for maintenance of the ‘warm-blooded’ or homoeothermic state. In normally active humans, this compartment of energy output approximates 40% of total energy expenditure. Many mammalian species utilize regulated decreases in temperature, such as hibernation or shallow torpor, as a means of energy conservation. Inherited forms of rodent obesity (ob/ob mouse, fa/fa rat) have lower core temperatures and withstand cold poorly. Obese humans, however, have normal core temperatures. This review addresses the role of core temperature in the metabolic economy of the obese state and raises the possibility that (i) lower temperatures may contribute to the increase in metabolic efficiency that accompanies weight loss in the obese; and (ii) that lower core temperatures may have initiated weight gain in the pre-obese state and that the normal temperatures in the obese may represent metabolic compensation to restore energy balance and limit further weight gain.