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Keywords:

  • A, D and Iλ-optimality;
  • approximate design;
  • mixture experiment;
  • multiple-objective optimal design;
  • optimal design

Summary

Mixture experiments are widely used in many industries and particularly in the manufacture of consumer products. Almost all work to date assumes a single study objective, which is unrealistic. Researchers may want to estimate model parameters and make predictions or extrapolations at the same time. We discuss design issues for determining the optimal proportions of the mixture components when there are two or more objectives in the study and there is a large sample size. We present a general methodology for constructing two types of dual-objective optimal design for mixture experiments and discuss the general applicability of the design strategy to more complicated types of mixture design problems, including mixture experiments.