Conflict of interest statement: No conflicts declared
THE ETHICS OF SHAM SURGERY IN PARKINSON'S DISEASE: BACK TO THE FUTURE?
Article first published online: 13 DEC 2011
© 2011 Blackwell Publishing Ltd.
Volume 27, Issue 4, pages 175–185, May 2013
How to Cite
SWIFT, T. and HUXTABLE, R. (2013), THE ETHICS OF SHAM SURGERY IN PARKINSON'S DISEASE: BACK TO THE FUTURE?. Bioethics, 27: 175–185. doi: 10.1111/j.1467-8519.2011.01931.x
Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms
- Issue published online: 14 APR 2013
- Article first published online: 13 DEC 2011
- sham surgery;
- research ethics;
- Parkinson's Disease;
Despite intense academic debate in the recent past over the use of ‘sham surgery’ control groups in research, there has been a recent resurgence in their use in the field of neurodegenerative disease. Yet the primacy of ethical arguments in favour of sham surgery controls is not yet established. Preliminary empirical research shows an asymmetry between the views of neurosurgical researchers and patients on the subject, while different ethical guidelines and regulations support conflicting interpretations. Research ethics committees faced with a proposal involving sham surgery should be aware of its ethical complexities. An overview of recent and current placebo-controlled surgical trials in the field of Parkinson's Disease is provided here, followed by an analysis of the key ethical issues which such trials raise.