This research examined children’s questions and the reactions to the answers they receive in conversations with adults. If children actively seek explanatory knowledge, they should react differently depending on whether they receive a causal explanation. Study 1 examined conversations following 6 preschoolers’ (ages 2–4 years) causal questions in naturalistic situations (using the Child Language Data Exchange System [CHILDES] database). Children more often agreed and asked follow-up questions following adult explanations and, conversely, more often reasked their original question and provided their own explanation following nonexplanations. Study 2 replicated these patterns within an experimental task in 42 children ages 3–5 years. Children’s reactions following explanatory versus nonexplanatory information confirm that young children are motivated to seek causal information actively and use specific conversational strategies to obtain it.