• 1
    Nelson M, Dockrell DD, Edwards S. on behalf of the BHIVA Guidelines Subcommittee. HIV Med 2011; 12 (Suppl. 2): 824.
  • 2
    Perfect JR, Dismukes WE, Dromer F et al. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Disease Society of America. Clin Infect Dis 2010; 50: 291322.
  • 3
    WHO Rapid advice: Diagnosis, prevention and management of cryptococcal disease in HIV-infected adults, adolescents and children. Available at (accessed 21 April 2012).
  • 4
    Leenders ACAP, Reiss P, Portegies P et al. Liposomal amphotericin B (AmBisome) compared with amphotericin B both followed by oral fluconazole in the treatment of AIDS-associated cryptococcal meningitis. AIDS 1997; 11: 14631471.
  • 5
    Hamill RJ, Sobel JD, El-Sadr W et al. Comparison of 2 doses of liposomal amphotericin B and conventional amphotericin B deoxycholate for treatment of AIDS-Associated acute cryptococcal meningitis: a randomized, double-blind clinical trial of efficacy and safety. Clin Infect Dis 2010; 51: 225232.
  • 6
    Bates DW, Su L, Yu DT et al. Mortality and costs of acute renal failure associated with amphotericin B therapy. Clin Infect Dis 2001; 32: 686693.
  • 7
    Bicanic T, Wood R, Meintjes G et al. High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial. Clin Infect Dis 2008; 47: 123130.
  • 8
    Kambugu A, Meya D, Rhein J et al. Outcomes of Cryptococcal Meningitis in Uganda Before and After the Availability of Highly Active Antiretroviral Therapy. Clin Infect Dis 2008; 46: 16941701.
  • 9
    Bicanic T, Muzoora C, Brouwer AE et al. Independent association between rate of clearance of infection and clinical outcome of HIV-associated cryptococcal meningitis: analysis of a combined cohort of 262 patients. Clin Infect Dis 2009; 49: 702709.
  • 10
    Longley N, Muzoora C, Taseera K et al. Dose response effect of high-dose fluconazole for HIV-associated cryptococcal meningitis in southwestern Uganda. Clin Infect Dis 2008; 47: 15561561.
  • 11
    Milefchik E, Leal MA, Haubrich R et al. Fluconazole alone or combined with flucytosine for the treatment of AIDS-associated cryptococcal meningitis. Med Mycol 2008; 46: 393395.
  • 12
    Nussbaum JC, Jackson A, Namarika D et al. Combination flucytosine and high-dose fluconazole compared with fluconazole monotherapy for the treatment of cryptococcal meningitis: a randomized trial in Malawi. Clin Infect Dis 2010; 50: 338344.
  • 13
    Macsween KF, Bicanic T, Brouwer AE et al. Lumbar drainage for control of raised cerebrospinal fluid pressure in cryptococcal meningitis: case report and review. J Infect 2005; 51: e221e224.