Thrombotic occlusion of the common carotid artery (CCA) in acute ischemic stroke treated with intravenous tissue plasminogen activator (TPA)
Article first published online: 23 JAN 2007
DOI: 10.1111/j.1468-1331.2006.01654.x
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How to Cite
Sharma, V. K., Tsivgoulis, G., Lao, A. Y., Flaster, M., Frey, J. L., Malkoff, M. D. and Alexandrov, A. V. (2007), Thrombotic occlusion of the common carotid artery (CCA) in acute ischemic stroke treated with intravenous tissue plasminogen activator (TPA). European Journal of Neurology, 14: 237–240. doi: 10.1111/j.1468-1331.2006.01654.x
Publication History
- Issue published online: 23 JAN 2007
- Article first published online: 23 JAN 2007
- Received 10 August 2006 Accepted 15 September 2006
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Keywords:
- Acute common carotid occlusion;
- cardioembolic;
- tandem lesions;
- thrombolysis
Although common carotid artery (CCA) occlusions are rare, acute clinical presentations vary from mild to devastating strokes primarily due to tandem occlusions in the intracranial arteries. Three patients with acute CCA occlusions were treated with systemic tissue plasminogen activator (TPA). Blood pressures were kept at the upper limits allowed with TPA therapy with fluid balance and the ‘head-down’ position. Recanalization occurred in intracranial vessels only. Marked early neurological improvement occurred in two of three patients. CCA occlusions should not be considered contra-indication to systemic thrombolysis.

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