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Table S1. Speech passage used to evaluate the natural speed of speech.

Table S2. Activities of daily living (ADL) questionnaire.

Table S3. The influence of the high and low dose therapies upon serum coenzyme Q10 and vitamin E levels.

Table S4. Comparison of changes in ICARS and kinetic scores in the therapy groups with cross sectional data.

Table S5. The influence of the high and low dose therapies upon various secondary end points.

Figure S1. Comparison of the baseline ICARS scores for the individual patients divided according to whether their ICARS scores showed an improvement (responders) or not (non responders) during the 2 years of the trial. The line indicates the score representing those patients dependent upon a wheelchair (above the line).

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Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.