The role of nutrients in the prevention and treatment of Alzheimer’s disease: methodology for a systematic review

Authors


Peter J. Whitehouse, Case Western Reserve University, Room 357C, Fairhill Center, 12200 Fairhill Road Cleveland, OH 44120, USA (tel.: 216 844 6448; fax: 216 844 6466;
e-mail: peter.whitehouse@case.edu)

Abstract

There is a large body of existing data on nutrition in Alzheimer’s disease (AD). We are conducting a systematic review of published scientific literature to determine the role of specific nutrients, both individually and in combination, in the prevention and treatment of AD. This will contribute towards a structured evidence base to help inform the clinical management of AD. The objective of the systematic review is to evaluate the strength of evidence from both observational cohort studies and randomized controlled trials on the role of fats, vitamins, antioxidants and other nutrients in the prevention and treatment of AD. We present here the methodology of our systematic review.

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