Impact of a weight loss program on migraine in obese adolescents
Article first published online: 29 MAY 2012
© 2012 The Author(s) European Journal of Neurology © 2012 EFNS
European Journal of Neurology
Volume 20, Issue 2, pages 394–397, February 2013
How to Cite
Verrotti, A., Agostinelli, S., D'Egidio, C., Di Fonzo, A., Carotenuto, M., Parisi, P., Esposito, M., Tozzi, E., Belcastro, V., Mohn, A. and Battistella, P. A. (2013), Impact of a weight loss program on migraine in obese adolescents. European Journal of Neurology, 20: 394–397. doi: 10.1111/j.1468-1331.2012.03771.x
- Issue published online: 12 JAN 2013
- Article first published online: 29 MAY 2012
- Manuscript Accepted: 24 APR 2012
- Manuscript Received: 14 JAN 2012
- weight loss
Background and purpose
Increased headache frequency and severity have been observed in obese populations, but the real impact of a weight loss treatment on headache has not been studied. We investigated this issue in a sample of obese adolescents.
In all, 135 migraineurs, aged 14–18 years, with body mass index (BMI) ≥97th percentile, participating in a 12-month-long program, were studied before and after treatment. The program included dietary education, specific physical training, and behavioral treatment.
Decreases in weight (P < 0.01), BMI (P < 0.01), waist circumference (P < 0.01), headache frequency (P < 0.01) and intensity (P < 0.01), use of acute medications (P < 0.05), and disability (P < 0.05) were observed at the end of the first 6-month period and were maintained through the second 6 months. Both lower baseline BMI and excess change in BMI were significantly associated with better migraine outcomes 12 months after the intervention program.
Significant improvements in both adiposity and headache data were observed in obese adolescents with migraine who participated in a 12-month-long interdisciplinary intervention program for weight loss. Initial body weight and amount of weight loss may be useful for clinicians to predict migraine outcomes.