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This article tests the empirical relationship between inequality and the protection of personal integrity rights using a cross-national time-series data set for 162 countries for the years 1980–2004. The data comprise measures of land inequality, income inequality, and a combined factor score for personal integrity rights protection, while the analysis controls for additional sets of explanatory variables related to development, political regimes, ethnic composition, and domestic conflict. The analysis shows robust support for the empirical relationship between income inequality and personal integrity rights abuse across the whole sample of countries as well as for distinct subsets, including non-communist countries and non-OECD countries. The hypothesized effect of land inequality is also born out by the data, although its effects are less substantial and less robust across different methods of estimation. Additional variables with explanatory weight include the level of income, democracy, ethnic fragmentation, domestic conflict, and population size. Sensitivity analysis suggests that the results are not due to reverse causation, misspecification or omitted variable bias. The analysis is discussed in the context of inequality and rights abuse in specific country cases and the policy implications of the results are considered in the conclusion.