Auditory event-related potentials and reaction times in migraine children


Giulia Buodo, Dipartimento di Psicologia Generale, Via Venezia, 8, 35131 Padova, Italy. Tel. + 39 049 827 6910, fax + 39 049 827 6600, e-mail


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Cognitive processing was investigated interictally in 18 children with migraine without aura and 18 age-matched controls by measuring event-related potentials (ERPs) and reaction times (RTs) during an acoustic oddball paradigm. Results showed that N100 amplitude evoked by frequent stimuli was significantly smaller in patients compared with controls. Habituation of target P300 amplitude was observed in patients but not in controls. Mean RTs were equivalent in the two  groups, but migraine  children made more errors than controls.