All authors participated in planning the protocol and revising the drafts of the manuscript. Specific tasks and responsibilities: general trial coordination (C.M.W., B.B., S.J.), statistical analysis and economic expertise (T.R., S.J., C.M.W., S.N.W.), overall medical and scientific responsibility (S.N.W.).
Cost-effectiveness of acupuncture treatment in patients with headache
Article first published online: 3 MAR 2008
Blackwell Publishing Ltd Cephalalgia, 2008
Volume 28, Issue 4, pages 334–345, April 2008
How to Cite
Witt, C., Reinhold, T., Jena, S., Brinkhaus, B. and Willich, S. (2008), Cost-effectiveness of acupuncture treatment in patients with headache. Cephalalgia, 28: 334–345. doi: 10.1111/j.1468-2982.2007.01504.x
- Issue published online: 3 MAR 2008
- Article first published online: 3 MAR 2008
- Received 19 July 2007, accepted 16 October 2007
- randomised controlled trial;
- routine care
The aim was to assess costs and cost-effectiveness of additional acupuncture treatment in patients with headache compared with patients receiving routine care alone. A randomized, controlled trial was conducted, including patients (≥18 years old) with primary headache (more than 12 months, at least two headaches/month). Outcome parameters were quality of life (Short Form 36), direct and indirect costs differences during the 3-month study period and the incremental cost-effectiveness ratio (ICER) of acupuncture treatment. A total of 3182 patients (1613 acupuncture; 1569 controls) with headache were included (77.4% women, mean age and standard deviation 42.6 ± 12.3; 22.6% men, 47.2 ± 13.4). Over 3 months costs were higher in the acupuncture group compared with the control [€857.47; 95% confidence interval 790.86, 924.07, vs. €527.34 (459.81, 594.88), P < 0.001, mean difference: €330.12 (235.27, 424.98)]. This cost increase was primarily due to costs of acupuncture [€365.64 (362.19, 369.10)]. The ICER was €11 657 per QALY gained. According to international cost-effectiveness threshold values, acupuncture is a cost-effective treatment in patients with primary headache.