A.C.W. and T.K. performed the statistical analyses. T.K. had full data access and takes full responsibility for the integrity of the data and the accuracy of the data analysis.
Body mass index, migraine, migraine frequency and migraine features in women
Article first published online: 15 OCT 2008
© Blackwell Publishing Ltd
Volume 29, Issue 2, pages 269–278, February 2009
How to Cite
Winter, A., Berger, K., Buring, J. and Kurth, T. (2009), Body mass index, migraine, migraine frequency and migraine features in women. Cephalalgia, 29: 269–278. doi: 10.1111/j.1468-2982.2008.01716.x
- Issue published online: 15 JAN 2009
- Article first published online: 15 OCT 2008
- Received 15 January 2008, accepted 9 June 2008
We evaluated the association of body mass index (BMI) with migraine and migraine specifics in a cross-sectional study of 63 467 women aged ≥ 45 years, of whom 12 613 (19.9%) reported any history of migraine and 9195 had active migraine. Compared with women without migraine and a BMI < 23 kg/m2, women with a BMI ≥ 35 kg/m2 had adjusted odds ratios (ORs) (95% confidence intervals) of 1.03 (0.95, 1.12) for any history of migraine. Findings were similar for active migraineurs. Women with a BMI of ≥ 35 kg/m2 had increased risk for low and high migraine frequency, with the highest estimate for women who reported daily migraine. Compared with women with the lowest associated risk (migraine frequency < 6 times/year; BMI between 27.0 and 29.9 kg/m2), women with a BMI ≥ 35 kg/m2 had an OR of daily migraine of 3.11 (1.12, 8.67). Among the women with active migraine, a BMI ≥ 35 kg/m2 was associated with increased risk of phonophobia and photophobia and decreased risk of a unilateral pain characteristic and migraine aura. Our data confirm previous findings that the association between BMI with migraine is limited to migraine frequency and specific migraine features.