Stressful major life events are associated with a higher frequency of cutaneous sensory symptoms: an empirical study of non-clinical subjects
Version of Record online: 16 JUN 2004
Journal of the European Academy of Dermatology and Venereology
Volume 18, Issue 5, pages 560–565, September 2004
How to Cite
Gupta, M. and Gupta, A. (2004), Stressful major life events are associated with a higher frequency of cutaneous sensory symptoms: an empirical study of non-clinical subjects. Journal of the European Academy of Dermatology and Venereology, 18: 560–565. doi: 10.1111/j.1468-3083.2004.00931.x
- Issue online: 2 JUL 2004
- Version of Record online: 16 JUN 2004
- Received: 13 November 2002, accepted 14 May 2003
Background Psychological stress resulting from stressful major life events is known to exacerbate a wide range of skin disorders.
Objective To examine the relationship between stressful major life events and dermatological symptoms among a non-clinical sample.
Design A cross-sectional survey.
Setting Community-based subjects from London, Ontario, Canada were recruited from the local university, schools and churches.
Participants Out of 600 consecutive, consenting volunteers 316 subjects [73 men and 243 women; age 38.7 ± 14.8 (mean ± SD) years; marital status 54% married; race 94%‘white’] completed the survey for this study. The exclusion criterion was a history of a major dermatological or medical disorder.
Main outcome measure The number of major life events experienced over the previous 6 months measured using the Social Readjustment Rating Scale (SRRS) of Holmes and Rahe, and the frequency and severity of a range of cutaneous symptoms (‘burning’, ‘crawling sensation’, ‘tingling’, ‘pricking’ or ‘pins and needles’, ‘pain’, ‘tenderness’ of skin, ‘numbness’, ‘moderate to severe itching’, and ‘easy bruising’) that the subject may have experienced over the previous month.
Results The most frequently reported body region affected was the scalp (59.5%) and the most frequently reported symptom was itching (69.3%). The total number of major life events experienced over the previous 6 months correlated with the severity of the individual cutaneous symptoms (0.22 ≤ Pearson r ≤ 0.41, P < 0.001) and with the total cutaneous symptom severity score (sum of all cutaneous severity ratings) (Pearson r = 0.40, P < 0.001). This correlation remained significant after the possible confounding effect of psychological factors on cutaneous symptoms was partialled out statistically (partial r = 0.19, P = 0.001).
Discussion We observed a direct correlation between the number of major life events experienced over the previous 6 months and cutaneous symptoms experienced over the previous 1 month by non-clinical subjects. The correlation remained significant after the effect of psychological factors was partialled out, suggesting that this relationship holds even if the subject does not acknowledge psychological distress in reaction to the major life event.