Psoriasis and diabetes: a population-based cross-sectional study

  1. AD Cohen1,2,3,*,
  2. J Dreiher1,2,
  3. Y Shapiro4,
  4. L Vidavsky1,
  5. DA Vardy2,3,
  6. B Davidovici5,
  7. J Meyerovitch1,6,7

Article first published online: 7 MAR 2008

DOI: 10.1111/j.1468-3083.2008.02636.x

Issue

Journal of the European Academy of Dermatology and Venereology

Journal of the European Academy of Dermatology and Venereology

Volume 22, Issue 5, pages 585–589, May 2008

Additional Information

How to Cite

Cohen, A., Dreiher, J., Shapiro, Y., Vidavsky, L., Vardy, D., Davidovici, B. and Meyerovitch, J. (2008), Psoriasis and diabetes: a population-based cross-sectional study. Journal of the European Academy of Dermatology and Venereology, 22: 585–589. doi: 10.1111/j.1468-3083.2008.02636.x

Author Information

  1. 1

    Research and Health Planning Department, Health Planning and Policy Wing, Clalit Health Services,Tel Aviv, Israel

  2. 2

    Southern District, Clalit Health Services,Tel Aviv, Israel

  3. 3

    Siaal Research Center for Family Medicine and Primary Care, Faculty of Health Sciences, Ben-Gurion University, Be’er Sheva, Israel

  4. 4

     Dermatology Department, Rabin Medical Center, Petah Tikva, Israel

  5. 5

    Dermatology Unit, Kaplan Medical Center, Rehovot, Israel

  6. 6

    Diabetes Services, Schneider Children's Medical Center, Petah Tikva, Israel

  7. 7

    Institute for Endocrinology and Diabetes, National Center for Childhood, Sackler School of Medicine, Tel Aviv University, Israel

* *Corresponding author, POB 4317, Omer 84965, Israel, tel. +972 50 6263848; fax +972 3 7608612; E-mail: arcohen@clalit.org.il

Publication History

  1. Issue published online: 7 MAR 2008
  2. Article first published online: 7 MAR 2008
  3. Received: 17 August 2007, Accepted 20 September 2007; DOI: 10.1111/j.1468-3083.2008.02636.x

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Abstract

Background  Previous reports have shown an association between psoriasis and the metabolic syndrome, but there are only a few studies on the association between psoriasis and diabetes.

Objectives  To study the association between psoriasis and diabetes.

Methods  A cross-sectional study was performed utilizing the database of Clalit Health Services (CHS). Patients who were diagnosed with psoriasis were compared with CHS enrolees without psoriasis regarding the prevalence of diabetes. Patients with diabetes were identified using the CHS chronic diseases registry. Chi-squared tests were used to compare categorical parameters. Logistic regression models were used for multivariate analyses.

Results  The study included 16 851 patients with psoriasis and 74 987 subjects without psoriasis (control patients). The proportion of diabetes was significantly higher in patients above 35 years (P < 0.05). The age-adjusted proportion of diabetes was significantly higher in psoriasis patients as compared to the control group [odds ratio (OR), 1.38, P < 0.05] and was similar in men and women (OR, 1.32, 1.45, respectively). A multivariate logistic regression model showed that psoriasis was significantly associated with diabetes, independently of age and gender (OR, 1.58, P < 0.001).

Conclusions  Our study supports previous reports of an association between psoriasis and diabetes. Dermatologists taking care of patients with psoriasis should be aware of this association and advise the patients to reduce additional risk factors such as smoking, hypertension or dyslipidemia.

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