These authors contributed equally to this work.
Prevalence and characteristics of psoriatic arthritis in Chinese patients with psoriasis
Article first published online: 23 FEB 2011
© 2011 The Authors. Journal of the European Academy of Dermatology and Venereology © 2011 European Academy of Dermatology and Venereology
Journal of the European Academy of Dermatology and Venereology
Volume 25, Issue 12, pages 1409–1414, December 2011
How to Cite
Yang, Q., Qu, L., Tian, H., Hu, Y., Peng, J., Yu, X., Yu, C., Pei, Z., Wang, G., Shi, B., Zhang, F., Zhang, Y. and Zhang, F. (2011), Prevalence and characteristics of psoriatic arthritis in Chinese patients with psoriasis. Journal of the European Academy of Dermatology and Venereology, 25: 1409–1414. doi: 10.1111/j.1468-3083.2011.03985.x
This study was supported by the grant from the Shandong Provincial Research Fund of Science and Technology (2007GG10002016).
Conflict of interest None declared.
- Issue published online: 14 NOV 2011
- Article first published online: 23 FEB 2011
- Received: 24 July 2010; Accepted: 12 January 2011
Background The prevalence and clinical characteristics of psoriatic arthritis (PsA) in patients with psoriasis vary widely in different countries and studies on Chinese population are rarely reported.
Objective The aim of this study was to evaluate the prevalence and clinical characteristics of PsA in a Chinese population of patients with psoriasis.
Methods A large cross-sectional observational study was conducted in our outpatient dermatology department and consecutive psoriatic patients were evaluated for PsA according to Classification of Psoriatic arthritis (CASPAR) criteria. Demographic and medical parameters were recorded.
Results Among 1928 patients with psoriasis, 112 patients (5.8%) had PsA, of which 92% was newly diagnosed. Oligoarthritis (48.2%) was the most common manifestation pattern, followed by spondylitis (26.8%), polyarthritis (19.6%) and classic distal interphalangeal (DIP) arthritis (5.4%). Enthesitis was present in 26.8% and dactylitis in 13.4% of the patients. Compared with patients without PsA, patients with PsA had more severe skin disease (mean PASI 9.7 vs. 6.0), higher frequency of nail changes (46.4% vs. 21.0%) and scalp involvement (90.2% vs. 76.4%).
Conclusion The findings are consistent with a low prevalence of PsA among patients with psoriasis in Asia and confirm a high percentage of undiagnosed cases with active arthritis among PsA patients in dermatologist’s office. Dermatologists should screen for PsA in their patients, especially those with risk characteristics and early signs.