Conflict of interest M. Le Maître, B. Crickx, J.P. Lacour consultant for La Roche-Posay. M. Bagot, J.-M. Chevallier, B. Cribier, M.-S. Doutre, F. Giordano-Labadie, B. Guillot, P. Joly, J.-L. Schmutz, P. Vabreshave been investigators for La Roche-Posay D. Bensimon appointed by Cosmetic Active France.
Validation of a clinical evaluation score for irritative dermatitis: SCOREPI
Article first published online: 22 AUG 2012
© 2012 The Authors. Journal of the European Academy of Dermatology and Venereology © 2012 European Academy of Dermatology and Venereology
Journal of the European Academy of Dermatology and Venereology
Volume 27, Issue 9, pages 1138–1142, September 2013
How to Cite
Le Maître, M., Crickx, B., Lacour, J.P., Bagot, M., Chevallier, J.-M., Cribier, B., Doutre, M.-S., Giordano-Labadie, F., Guillot, B., Joly, P., Schmutz, J.-L., Vabres, P. and Bensimon, D. (2013), Validation of a clinical evaluation score for irritative dermatitis: SCOREPI. Journal of the European Academy of Dermatology and Venereology, 27: 1138–1142. doi: 10.1111/j.1468-3083.2012.04678.x
Funding source This work was supported by Laboratoires La Roche-Posay.
- Issue published online: 28 JUL 2013
- Article first published online: 22 AUG 2012
- Received: 4 April 2012; Accepted: 13 July 2012
Background Most dermatological conditions can be evaluated using validate clinical scores, no such tool is available for irritant contact dermatitis (ICD).
Objective To create and validate a grid-based ICD severity score.
Methods Three dermatologists developed the SCOre de REparation de l’EPIderme (SCOREPI) grid. Two studies were conducted to validate the SCOREPI. A cross-sectional study assessed the intra- and inter-observer error associated with using the SCOREPI. Each investigator received 15 min of training on proper use of the SCOREPI. A computer displayed a series of 20 photos of ICD, each of which were repeated three times in a randomized order. The prospective study assessed the correlation between SCOREPI with the severity of clinical symptoms as well as the sensitivity of the score to changes in ICD in response to topical treatment.
Results The SCOREPI took an average of 35 ± 5 s to be completed and was characterized by an excellent intra-observer and moderate inter-observer reproducibility (intra-class correlation coefficient = 0.93 and 0.74, respectively). Significant divergence was observed between the physicians’ assessment of estimated surface (P = 0.04), the presence of erythema (P < 0.0001) and the number of deep cracks (P = 0.0008). In the prospective analysis of patients, SCOREPI was correlated with tightness (r = 0.45; P < 0.0001), pain (r = 0.45; P < 0.0001), burning (r = 0.42; P < 0.0001), and pruritus (r = 0.28; P = 0.0055). SCOREPI decreased considerably during follow-up from 10.45 ± 4.61 to 4.82 ± 4.15 (P < 0.0001).
Conclusion The SCOREPI is easy to use, sensitive to change, and characterized by high intra- and moderate inter-observer reliability.