We thank Dr Mark Hamer, University College London, UK, for providing professional suggestion on cardiovascular health science.
The association between chronic psychosocial stress, allostatic load, and vascular health in asymptomatic young men: A pilot study using a novel finger arterial stiffness index1
Article first published online: 10 MAY 2011
© Japanese Psychological Association 2011.
Japanese Psychological Research
Special Issue: Psychobiological approaches to stress and health: Recent progress. Guest Editor: Mark Hamer & Editor: Akira Tsuda
Volume 53, Issue 2, pages 140–154, May 2011
How to Cite
TANAKA, G., KATO, Y., MATSUMURA, K., HORIGUCHI, M., OGASAWARA, H. and SAWADA, Y. (2011), The association between chronic psychosocial stress, allostatic load, and vascular health in asymptomatic young men: A pilot study using a novel finger arterial stiffness index. Japanese Psychological Research, 53: 140–154. doi: 10.1111/j.1468-5884.2011.00461.x
This study was supported in part by a Grant-in-Aid for Scientific Research (B) from Japan Society for the Promotion of Science (Grant No. 21300252) awarded to Gohichi Tanaka.
- Issue published online: 10 MAY 2011
- Article first published online: 10 MAY 2011
- (Received October 4, 2010; accepted January 22, 2011)
- arterial stiffness;
- small artery and arteriole;
- allostatic load;
- psychosocial stress;
- cardiovascular health
A novel index of finger arterial stiffness (FSI) was tested in terms of the relationship with risk markers for preclinical cardiovascular disease. In addition, we examined if the association between psychosocial factors and FSI was explained by allostatic load markers in 37 healthy young men aged 24.8 ± 4.0 years. The FSI was devised based on an exponential model of the finger arterial pressure-volume relationship. The allostatic load index (ALI) as a cumulative risk marker was defined by the mean of standard scores for nine variables: resting systolic and diastolic blood pressure, waist/hip ratio, high-density lipoprotein cholesterol (HDL-C), total cholesterol/HDL-C ratio, triglycerides, hemoglobin A1c, insulin resistance, and high sensitivity C-reactive protein (CRP). Partial correlations controlling for age were significant for FSI with HDL-C (r = −.36), CRP (r = .39), ALI (r = .40), unhealthy overall eating habits (r = .34), hostility using the Buss-Perry Aggression Questionnaire (r = .38), and manageability in Sense of Coherence (r = −.38). In conclusion, FSI seems to be associated with vascular proinflammation as well as with overall physiological dysregulation and allostatic load. These associations were moderated by eating lifestyle and psychosocial stress.