Rhodococcus equi infection in non-HIV-infected patients. Two case reports and review
Article first published online: 2 JUN 2009
1997 European Society of Clinical Microbiology and Infectious Diseases
Clinical Microbiology and Infection
Volume 3, Issue 1, pages 12–18, February 1997
How to Cite
Farina, C., Ferruzzi, S., Mamprin, F. and Vailati, F. (1997), Rhodococcus equi infection in non-HIV-infected patients. Two case reports and review. Clinical Microbiology and Infection, 3: 12–18. doi: 10.1111/j.1469-0691.1997.tb00245.x
- Issue published online: 2 JUN 2009
- Article first published online: 2 JUN 2009
- Accepted 14 August 1996
- Rhodococcus equi
Objective: To review two recent cases in HIV-negative subjects in the light of literature reports (52 patients without HIV infection till 1994).
Method: Epidemiology (animal contacts, risk factors, year, country), clinical presentation, diagnostic methods (X-ray, tomography, microbiological techniques), therapeutic approach (antibiotics, surgery) and outcome were evaluated on the basis of clinical literature reports.
Results: Tumors constituted an important predisposing factor and less frequently hepatobiliary pathology, rheumatologic diseases, iatrogenic causes, psychiatric pathology and trauma. Exposure to animals was reported by 55% of the patients. Pneumonia and pleurisy, without preferential localization, were detected in 50% of the patients. Etiologic diagnosis was usually obtained after an invasive collection. Combined medical therapy and surgery were required by 27.8% of the patients, and 16.7% of the patients died.
Conclusions: In recent years the number of Rhodococcus equi cases has been rising also in HIV-negative patients. The infection is ubiquitous. Accurate diagnosis and the prompt selection of the most appropriate therapy depend on close cooperation between clinicians and microbiologists.