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Increasing erythromycin resistance among group A streptococci causing tonsillitis in a tertiary care hospital in southern India
Article first published online: 10 MAR 2005
DOI: 10.1111/j.1469-0691.2005.01100.x
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How to Cite
Brahmadathan, K. N., Anitha, P. and Gladstone, P. (2005), Increasing erythromycin resistance among group A streptococci causing tonsillitis in a tertiary care hospital in southern India. Clinical Microbiology and Infection, 11: 335–337. doi: 10.1111/j.1469-0691.2005.01100.x
Publication History
- Issue published online: 10 MAR 2005
- Article first published online: 10 MAR 2005
- Original Submission: 4 May 2004; Revised Submission: 14 October 2004; Accepted: 1 December 2004
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Keywords:
- Erythromycin resistance;
- group A streptococci;
- macrolides;
- penicillin;
- resistance;
- streptococci
Abstract
Group A streptococci (GAS) (n = 1313) isolated from patients with clinical symptoms of pharyngitis or tonsillitis attending a tertiary care hospital in southern India during 1986–2002 were tested for susceptibility to penicillin and erythromycin. The overall erythromycin resistance rate was 2.7% (n = 36). During 1986–1993, erythromycin resistance was observed in only one (2%) isolate in 1987, but reappeared in 1994 (2.7%), increased to 5.8% in 1999, and reached a maximum frequency of 13.8% in 2002. All isolates were susceptible to penicillin. The data indicate the need for continued surveillance of susceptibility patterns among GAS isolates in order to monitor the development of antibiotic resistance.