Hormographiella aspergillata: an emerging mould in acute leukaemia patients?
Article first published online: 18 MAY 2010
© 2010 The Authors. Journal Compilation © 2010 European Society of Clinical Microbiology and Infectious Diseases
Clinical Microbiology and Infection
Volume 17, Issue 2, pages 273–277, February 2011
How to Cite
Conen, A., Weisser, M., Hohler, D., Frei, R. and Stern, M. (2011), Hormographiella aspergillata: an emerging mould in acute leukaemia patients?. Clinical Microbiology and Infection, 17: 273–277. doi: 10.1111/j.1469-0691.2010.03266.x
- Issue published online: 20 JAN 2011
- Article first published online: 18 MAY 2010
- Original Submission: 15 February 2010; Revised Submission: 17 April 2010; Accepted: 29 April 2010 Editor: E. Roilides Article published online: 18 May 2010
- mould infection;
- non-Aspergillus mould;
- stem cell transplantation
Clin Microbiol Infect 2011; 17: 273–277
We describe three invasive mould infections due to Hormographiella aspergillata occurring within 1 year in patients undergoing treatment for acute leukaemia. All patients presented with pulmonary infiltrates; one patient additionally had cerebral and ocular involvement. Diagnostic procedures included bronchoalveolar lavage in all, and video-assisted thoracoscopic surgery in two patients. Susceptibility testing was performed by E-test and detected low minimal inhibitory concentrations for voriconazole and amphotericin B. All patients received systemic antifungal therapy; however, all of them died. Despite this cluster of three cases of an unusual mould infection, no hospital source was detected.