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Risk factors for severe complications of the novel influenza A (H1N1): analysis of patients hospitalized in Italy

  1. M. Bassetti1,
  2. A. Parisini1,
  3. A. Calzi1,
  4. F. M. Bobbio Pallavicini2,
  5. G. Cassola3,
  6. S. Artioli4,
  7. M. Anselmo5,
  8. G. Pagano6,
  9. G. Rezza7,
  10. C. Viscoli1,
  11. for the Ligurian H1N1 Collaborative Group

Article first published online: 1 JUN 2010

DOI: 10.1111/j.1469-0691.2010.03275.x

Issue

Clinical Microbiology and Infection

Clinical Microbiology and Infection

Volume 17, Issue 2, pages 247–250, February 2011

Additional Information

How to Cite

Bassetti, M., Parisini, A., Calzi, A., Pallavicini, F. M. B., Cassola, G., Artioli, S., Anselmo, M., Pagano, G., Rezza, G., Viscoli, C. and for the Ligurian H1N1 Collaborative Group (2011), Risk factors for severe complications of the novel influenza A (H1N1): analysis of patients hospitalized in Italy. Clinical Microbiology and Infection, 17: 247–250. doi: 10.1111/j.1469-0691.2010.03275.x

Author Information

  1. 1

     Infectious Diseases Division, San Martino Hospital and University of Genoa School of Medicine, Genoa

  2. 2

     Intensive Care Unit, San Martino Hospital, Genoa

  3. 3

     Infectious Diseases Division, EO Galliera, Genova

  4. 4

     Infectious Diseases Division, S. Andrea Hospital, Spezia

  5. 5

     Infectious Diseases Division, San Paolo Hospital, Savona

  6. 6

     Infectious Diseases Division, S. Martino Hospital, Genova

  7. 7

     Department of Infectious Diseases, Istituto Superiore di Sanità, Roma, Italy

*Corresponding author and reprint requests: M. Bassetti, Clinica Malattie Infettive, AOU San Martino, L.go R.Benzi 10, 16132 Genova, Italy E-mail: matteo.bassetti@hsanmartino.it

Publication History

  1. Issue published online: 20 JAN 2011
  2. Article first published online: 1 JUN 2010
  3. Original Submission: 22 December 2009; Revised Submission: 13 March 2010; Accepted: 8 April 2010 Editor: G. Antonelli Article published online: 1 June 2010

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Keywords:

  • Complications;
  • H1N1;
  • pneumonia;
  • risk factors

Clin Microbiol Infect 2011; 17: 247–250

Abstract

Eighty-one patients affected by the novel influenza A (H1N1), hospitalized in North-western Italy, were studied. The median age was 32 years (range 1–81 years). Fifty-six (69%) had an underlying medical condition, including lung disorders (asthma or chronic obstructive pulmonary disease) in 34% and obesity in 25%. Fifty percent of them had pneumonia, 12% were admitted to the intensive care unit and 3% died. Antiviral treatment was initiated in 75% of patients started within 48 h. Older age and lung and neurocognitive disorders were associated with severe disease and death.

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