Emergence of five kinds of aminoglycoside-modifying enzyme genes simultaneously in a strain of multidrug-resistant Escherichia coli in China


Corresponding author: W. Xing-Bei, Department of Medical Laboratory, Ningbo First Hospital, No.59, Liuting Street, Ningbo, 315010 Zhejiang, China.
E-mail: wxb6006@hotmail.com


Clin Microbiol Infect 2012; 18: E11–E12


A strain of Escherichia coli was positive for 5 aminoglycoside modifying enzyme genes (aac(3)-I, aac(6′)-Ib-cr, ant(3″″)-I, aadA5, and aph(3′)-I) in PCR assays. And these positive genes confer resistance to aminoglycosides (gentamicin and tobramycin). This is the first report of emergence of five kinds of aminoglycoside-modifying enzymes genes simultaneously in E. coli worldwide.