• 1
    Centers for Disease Control and Prevention. Surveillance for Lyme disease – United States, 1992–2006. MMWR Morb Mortal Wkly Rep2008; 57: 19.
  • 2
    Wormser GP, Dattwyler RJ, Shapiro ED et al. The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis2006; 43: 10891134.
  • 3
    Aguero-Rosenfeld ME, Wang G, Schwartz I, Wormser GP. Diagnosis of Lyme borreliosis. Clin Microbiol Rev2005; 18: 484509.
  • 4
    Centers for Disease Control and Prevention. Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease. MMWR Morb Mortal Wkly Rep1995; 44: 590591.
  • 5
    Branda JA, Linskey K, Kim YA, Steere AC, Ferraro MJ. Two-tiered antibody testing for Lyme disease with use of 2 enzyme immunoassays, a whole-cell sonicate enzyme immunoassay followed by a VlsE C6 peptide enzyme immunoassay. Clin Infect Dis2011; 53: 541547.
  • 6
    Branda JA, Aguero-Rosenfeld ME, Ferraro MJ, Johnson BJ, Wormser GP, Steere AC. 2-tiered antibody testing for early and late Lyme disease using only an immunoglobulin G blot with the addition of a VlsE band as the second tier test. Clin Infect Dis2010; 50: 2026.
  • 7
    Weinstein A. Editorial commentary: laboratory testing for Lyme disease: time for a change?Clin Infect Dis2008; 47: 196197.
  • 8
    Wormser GP. Clinical practice. early Lyme disease. N Engl J Med2006; 354: 27942801.
  • 9
    Aguero-Rosenfeld ME, Nowakowski J, McKenna DF, Carbonaro CA, Wormser GP. Serodiagnosis in early Lyme disease. J Clin Microbiol1993; 31: 30903095.
  • 10
    Aguero-Rosenfeld ME, Nowakowski J, Bittker S, Cooper D, Nadelman RB, Wormser GP. Evolution of the serologic response to Borrelia burgdorferi in treated patients with culture-confirmed erythema migrans. J Clin Microbiol1996; 34: 19.
  • 11
    Feder HM, Johnson BJ, O’Connell S et al. A critical appraisal of “chronic Lyme disease”. N Engl J Med2007; 357: 14221430.
  • 12
    Goosens HA, Nohlmans MK, Van Den Bogaard AE. Epstein-Barr virus and cytomegalovirus infections cause false-positive results in IgM two-test protocol for early Lyme borreliosis. Infection1999; 27: 231.
  • 13
    Tugwell P, Dennis DT, Weinstein A et al. Laboratory evaluation in the diagnosis of Lyme disease. Ann Intern Med1997; 127: 11091123.
  • 14
    Wormser GP, Nowakowski J, Nadelman RB, Visintainer P, Levin A, Aguero-Rosenfeld ME. Impact of clinical variables on Borrelia burgdorferi-specific antibody seropositivity in acute-phase sera from patients in North America with culture-confirmed early Lyme disease. Clin Vaccine Immunol2008; 15: 15191522.
  • 15
    Liang FT, Steere AC, Marques AR, Johnson BJB, Miller JN, Philipp MT. Sensitive and specific serodiagnosis of Lyme disease by enzyme-linked immunosorbent assay with a peptide based on an immunodominant conserved region of Borrelia burgdorferi VlsE. J Clin Microbiol1999; 37: 39903996.