• 1
    Yu J, Kochanek KD, Murphy SL, Tejada-Vera B. Deaths: final data for 2006. Natl Vital Stat Rep 2009; 57: 1134.
  • 2
    Madsen KM, Schonheyder HC, Kristensen B, Sorensen HT. Secular trends in incidence and mortality of bacteraemia in a Danish County 1981–1994. APMIS 1999; 107: 346352.
  • 3
    Uslan DZ, Crane SJ, Steckelberg JM et al. Age- and sex-associated trends in bloodstream infections. A population-based study in Olmsted County, Minnesota. Arch Intern Med 2007; 167: 834839.
  • 4
    Skogberg K, Lyytikäinen O, Ruutu P, Ollgren J, Nuorti JP. Increase in bloodstream infections in Finland, 1995–2002. Epidemiol Infect 2008; 136: 108114.
  • 5
    Wilson J, Elgohari S, Livermore DM et al. Trends among pathogens reported as causing bacteraemia in England 2004–2008. Clin Microbiol Infect 2011; 17: 451458.
  • 6
    Reacher MH, Shah A, Livermore DM et al. Bacteraemia and antibiotic resistance of its pathogens reported in England and Wales between 1990 and 1998: trend analysis. BMJ 2000; 320: 213216.
  • 7
    Curns AT, Holman RC, Sejvar JJ, Owings MF, Schonberger LB. Infectious disease hospitalizations among older adults in the United States from 1990 through 2002. Arch Intern Med 2005; 165: 25142520.
  • 8
    Brun-Buisson C, Doyon F, Carlet J. Bacteremia and severe sepsis in adults: a multicenter prospective survey in ICUs and wards of 24 hospitals. French Bacteremia-Sepsis Study Group. Am J Respir Crit Care Med 1996; 154 (3 Pt 1): 617624.
  • 9
    Weinstein MP, Towns ML, Quartey SM et al. The clinical significance of positive blood cultures in the 1990s: a prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults. Clin Infect Dis 1997; 24: 584602.
  • 10
    Bouza E, Pérez-Molina J, Muñoz P. Report of ESGNI-001 and ESGNI-002 studies. Bloodstream infections in Europe. Clin Microbiol Infect 1999; 5 (Suppl 2): 112.
  • 11
    Diekema DJ, Beekmann SE, Chapin KC, Morel KA, Munson E, Doern GV. Epidemiology and outcome of nosocomial and community-onset bloodstream infection. J Clin Microbiol 2003; 41: 36553660.
  • 12
    Søgaard M, Engebjerg MC, Lundbye-Christensen S, Schønheyder HC. Changes in blood culture methodology have an impact on time trends of bacteremia: a 26-year regional study. Epidemiol Infect 2011; 139: 772776.
  • 13
    Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 348: 15461554.
  • 14
    Karlsson S, Varpula M, Ruokonen E et al. Incidence, treatment, and outcome of severe sepsis in ICU-treated adults in Finland: the Finnsepsis study. Intensive Care Med 2007; 33: 435443.
  • 15
    Klemets P, Lyytikäinen O, Ruutu P, Ollgren J, Nuorti JP. Invasive pneumococcal infections among persons with and without underlying medical conditions: implications for prevention strategies. BMC Infect Dis 2008; 8: 96.
  • 16
    Laupland KB, Gregson DB, Church DL, Ross T, Pitout JDD. Incidence, risk factors and outcomes of Escherichia coli bloodstream infections in a large Canadian region. Clin Microbiol Infect 2008; 14: 10411047.
  • 17
    Laupland KB, Ross T, Gregson DB. Staphylococcus aureus bloodstream infections: risk factors, outcomes, and the influence of methicillin resistance in Calgary, Canada, 2000–2006. J Infect Dis 2008; 198: 336343.
  • 18
    Lyytikäinen O, Ruotsalainen E, Järvinen A, Valtonen V, Ruutu P. Trends and outcome of nosocomial and community-acquired bloodstream infections due to Staphylococcus aureus in Finland, 1995–2001. Eur J Clin Microbiol Infect Dis 2005; 24: 399404.
  • 19
    Johnson AP, Pearson A, Duckworth G. Surveillance and epidemiology of MRSA bacteraemia in the UK. J Antimicrob Chemother 2005; 56: 455462.
  • 20
    De Kraker ME, Wolkewitz M, Davey PG, Grundmann H, BURDEN Study Group. Clinical impact of antimicrobial resistance in European hospitals: excess mortality and length of hospital stay related to methicillin-resistant Staphylococcus aureus bloodstream infections. Antimicrob Agents Chemother 2011; 55: 15981605, Epub.
  • 21
    Garnacho-Montero J, Aldabo-Pallas T, Garnacho-Montero C et al. Timing of adequate antibiotic therapy is a greater determinant of outcome than are TNF and IL-10 polymorphisms in patients with sepsis. Crit Care 2006; 10: R111.
  • 22
    Kumar A, Roberts D, Wood KE et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 2006; 34: 15891596.
  • 23
    McDonald JR, Friedman ND, Stout JE, Sexton DJ, Kaye KS. Risk factors for ineffective therapy in patients with bloodstream infection. Arch Intern Med 2005; 165: 308313.
  • 24
    Garnacho-Montero J, Ortiz-Leyba C, Herrera-Melero I et al. Mortality and morbidity attributable to inadequate empirical antimicrobial therapy in patients admitted to the ICU with sepsis: a matched cohort study. J Antimicrob Chemother 2008; 61: 436441.
  • 25
    Centers for Disease Control Prevention (CDC). Vital signs: central line-associated blood stream infections—United States, 2001, 2008, and 2009. Morb Mortal Wkly Rep 2011; 60: 243248.
  • 26
    Lyytikäinen O, Lumio J, Sarkkinen H et al. Nosocomial bloodstream infections in Finnish hospitals during 1999–2000. Clin Infect Dis 2002; 35: e14e19.