SEARCH

SEARCH BY CITATION

References

  • 1
    Hare S , Smith SJ , Métifiot M et al. Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572) . Mol Pharmacol 2011 ; 80 : 565572 .
  • 2
    Hightower KE , Wang R , Deanda F et al. Dolutegravir (S/GSK1349572) exhibits significantly slower dissociation than raltegravir and elvitegravir from wild-type and integrase inhibitor-resistant HIV-1 integrase-DNA complexes . Antimicrob Agents Chemother 2011 ; 55 : 45524559 .
  • 3
    Kobayashi M , Yoshinaga T , Seki T et al. In Vitro antiretroviral properties of S/GSK1349572, a next-generation HIV integrase inhibitor . Antimicrob Agents Chemother 2011 ; 55 : 813821 .
  • 4
    Bar-Magen T , Sloan RD , Donahue DA et al. Identification of novel mutations responsible for resistance to MK-2048, a second-generation HIV-1 integrase inhibitor . J Virol 2010 ; 84 : 92109216 .
  • 5
    Canducci F , Ceresola ER , Boeri E et al. Cross-resistance Profile of the Novel Integrase Inhibitor Dolutegravir (S/GSK1349572) Using Clonal Viral Variants Selected in Patients Failing Raltegravir . J Infect Dis 2011 ; 204 : 18111815 .
  • 6
    Blanco JL , Varghese V , Rhee SY , Gatell JM , Shafer RW . HIV-1 integrase inhibitor resistance and its clinical implications . J Infect Dis 2011 ; 203 : 12041214 .
  • 7
    Garrido C , Soriano V , Geretti AM et al. Resistance associated mutations to dolutegravir (S/GSK1349572) in HIV-infected patients--impact of HIV subtypes and prior raltegravir experience . Antiviral Res 2011 ; 90 : 164167 .
  • 8
    Malet I , Wirden M , Fourati S et al. Prevalence of resistance mutations related to integrase inhibitor S/GSK1349572 in HIV-1 subtype B raltegravir-naive and –treated patients . J Antimicrob Chemother 2011 ; 66 : 14811483 .
  • 9
    Ceccherini-Silberstein F , Malet I , D’Arrigo R , Antinori A , Marcelin AG , Perno CF . Characterization and structural analysis of HIV-1 integrase conservation . AIDS Rev 2009 ; 11 : 1729 .
  • 10
    Garrido C , Geretti AM , Zahonero N et al. Integrase variability and susceptibility to HIV integrase inhibitors: impact of subtypes, antiretroviral experience and duration of HIV infection . J Antimicrob Chemother 2010 ; 65 : 320326 .