*Clinical Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20205, USA.
A genetic polymorphism of a human urinary mucin
Article first published online: 28 SEP 2007
Annals of Human Genetics
Volume 47, Issue 4, pages 263–269, October 1983
How to Cite
KARLSSON, S., SWALLOW, D. M., GRIFFITHS, B., CORNEY, G., HOPKINSON, D. A., DAWNAY, A. and CARTRON, J. P. (1983), A genetic polymorphism of a human urinary mucin. Annals of Human Genetics, 47: 263–269. doi: 10.1111/j.1469-1809.1983.tb00995.x
- Issue published online: 28 SEP 2007
- Article first published online: 28 SEP 2007
We report here a novel genetically determined polymorphism of a human urinary mucin which is demonstrable by the separation technique of SDS polyacrylamide gel electrophoresis, followed by detection with radio-iodinated lectins. The mucins are demonstrable using various lectins but the polymorphism is most easily recognized using peanut agglutinin and we therefore propose to designate this new genetic locus PUM (peanut-reactive urinary mucin). Four common alleles have been identified and an autosomal codominant mode of inheritance has been found in the families studied so far.