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In search of the Pre- and Post-Neolithic Genetic Substrates in Iberia: Evidence from Y-Chromosome in Pyrenean Populations

  1. A. M. López-Parra1,
  2. L. Gusmão2,
  3. L. Tavares2,
  4. C. Baeza1,
  5. A. Amorim2,3,
  6. M. S. Mesa4,
  7. M. J. Prata2,3,
  8. E. Arroyo-Pardo1,*

Article first published online: 18 SEP 2008

DOI: 10.1111/j.1469-1809.2008.00478.x

Issue

Annals of Human Genetics

Annals of Human Genetics

Volume 73, Issue 1, pages 42–53, January 2009

Additional Information

How to Cite

López-Parra, A. M., Gusmão, L., Tavares, L., Baeza, C., Amorim, A., Mesa, M. S., Prata, M. J. and Arroyo-Pardo, E. (2009), In search of the Pre- and Post-Neolithic Genetic Substrates in Iberia: Evidence from Y-Chromosome in Pyrenean Populations. Annals of Human Genetics, 73: 42–53. doi: 10.1111/j.1469-1809.2008.00478.x

Author Information

  1. 1

    Departamento de Toxicología y Legislación Sanitaria, Facultad de Medicina, Universidad Complutense de Madrid, Spain

  2. 2

    IPATIMUP, Institute of Pathology and Immunology of University of Porto, Portugal

  3. 3

    Faculty of Sciences, University of Porto, Porto, Portugal

  4. 4

    Unidad Docente de Antropología, Departamento de Zoología y Antropología Física, Facultad de Ciencias Biológicas, Universidad Complutense de Madrid, Spain

* *Corresponding author: Dr. Eduardo Arroyo-Pardo, Laboratorio de Genética Forense y Genética de Poblaciones, Departamento de Toxicología y Legislación Sanitaria, Facultad de Medicina, Universidad Complutense de Madrid, E-28040, Madrid, Spain. E-mail: earroyop@med.ucm.es

Publication History

  1. Issue published online: 1 JAN 2009
  2. Article first published online: 18 SEP 2008
  3. Received: 7 May 2008Accepted: 21 July 2008

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Keywords:

  • Pyrenees;
  • Y-chromosome;
  • haplogroups;
  • haplotypes;
  • Iberia

Summary

The male-mediated genetic legacy of the Pyrenean population was assessed through the analysis of 12 Y-STR and 27 Y-SNP loci in a sample of 169 males from 5 main geographical areas in the Spanish Pyrenees: Cinco Villas (Western Pyrenees), Jacetania and Valle de Arán (Central Pyrenees) and Alto Urgel and Cerdaña (Eastern Pyrenees). In the Iberian context, the Pyrenean samples present some specificities, being characterizeded by a high proportion of chromosomes R1b1b2-M269 (including the usually uncommon R1b1b2d-SRY2627 and R1b1b2c-M153 types) or I2a2-M26 and low proportions of other haplogroups. Our results indicate that an old pre-Neolithic substrate is preponderant in populations of the whole Pyrenean fringe. However, AMOVA revealed a high level of substructure within Pyrenean populations, partially explained by drift effects as well as by the signature of an ancient genetic differentiation between Western and Eastern Pyrenees.

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