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Supplementary Methods

Table S1 Minor allelic frequencies of SNP markers for each population.

Table S2 TaqMan probes sequences and labeling.

Table S3 PCR primers.

Table S4 PCR reaction mixtures.

Table S5 PCR program.

Table S6 Comparison of anthropometric clinical and metabolic parameters between the control and T2DM subjects.

Table S7 Comparison of anthropometric clinical and metabolic parameters between the control and MS subjects.

Table S8 Evaluation of Hardy–Weinberg equilibrium for each SNP marker.

Table S9 Association of adiponectin and resistin gene polymorphisms with T2DM risk.

Table S10 Association of adiponectin and resistin gene polymorphisms with MS risk.

Table S11 Association of adiponectin gene polymorphisms with T2DM and MS risk for each ethnic group.

Table S12 Association of resistin gene polymorphisms with T2DM and MS risk for each ethnic group.

Figure S1 Genetic architecture and location of the SNPs at the ADIPOQ and RETN loci.

Figure S2 Checking for homogeneity of covariates to match the subject groups.

Figure S3 Standard curve for ELISA adiponectin and resistin.

Figure S4 Allelic discrimination plots for TaqMan Real-Time PCR.

Figure S5 UV illumination photos of gel electrophoresis of purified PCR products.

Figure S6 Chromatogram of sequencing results for SNP+45T>G at the ADIPOQ locus.

Figure S7 Chromatogram of sequencing results for SNP+276G>T at the ADIPOQ locus.

Figure S8 Chromatogram of sequencing results for SNP+639T>C at the ADIPOQ locus.

Figure S9 Chromatogram of sequencing results for SNP+1212A>G at the ADIPOQ locus.

Figure S10 Chromatogram of sequencing results for SNP-420C>G at the RETN locus.

Figure S11 Chromatogram of sequencing results for SNP+299G>A at the RETN locus.

Supplementary Notes

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