[ Phylogeny and timescale of mammalian orders defined by nuclear and mitochondrial DNA sequence data. The branches are drawn proportional to divergence time (per million years) based on a consensus of recent phylogenetic and divergence time estimates from the literature: (Hasegawa et al., 2003; Nilsson et al., 2003, 2004; Springer et al., 2003; Woodburne et al., 2003; Roca et al., 2004; Teeling et al., 2005; van Rheede et al., 2006). Red arrows indicate those lineages/species for which a whole genome sequencing effort is finished or underway. ]
An example of these potential insights was provided recently when a group of investigators explored the question of whether the high proportion of pseudogenes in humans is shared with other primates (Gilad et al., 2004). Random sequencing of approximately 100 OR genes in other primates revealed that after humans, apes and Old World monkeys have significantly higher proportions of OR pseudogenes (> 30%) than New World monkeys or prosimians, which have less than 20% like mouse.
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