Conflict of interest statement: No conflicts declared.
Perplexities and provocations of eating disorders
Article first published online: 29 JAN 2009
© 2009 The Author. Journal compilation © 2009 Association for Child and Adolescent Mental Health
Journal of Child Psychology and Psychiatry
Volume 50, Issue 1-2, pages 163–169, January/February 2009
How to Cite
Halmi, K. A. (2009), Perplexities and provocations of eating disorders. Journal of Child Psychology and Psychiatry, 50: 163–169. doi: 10.1111/j.1469-7610.2008.01983.x
- Issue published online: 29 JAN 2009
- Article first published online: 29 JAN 2009
- Manuscript accepted 21 April 2008
- Anorexia nervosa;
- bulimia nervosa;
Background: Etiological hypotheses of eating disorders, anorexia nervosa and bulimia nervosa have not produced informative research for predictably effective treatment.
Methods: The rationale for applying a model of allostasis, a dysregulation of reward circuits with activation of brain and hormonal stress responses to maintain apparent stability, is developed for eating disorders.
Results: The neurotransmitter systems involved in the allostatic state of a reward system in anorexia nervosa and bulimia nervosa may be similar to those present in drug addiction.
Conclusion: The biological vulnerabilities underlying the unique features of eating disorders should be intensively investigated with the advancing techniques in genetics and neuroimaging. Preventing chronicity with early diagnosis and adequate treatment before age 18 is necessary.