Conflict of interest statement: No conflicts declared.
Deconstructing the PDD clinical phenotype: internal validity of the DSM-IV
Article first published online: 29 JUN 2009
© 2009 The Authors. Journal compilation © 2009 Association for Child and Adolescent Mental Health
Journal of Child Psychology and Psychiatry
Volume 50, Issue 10, pages 1246–1254, October 2009
How to Cite
Lecavalier, L., Gadow, K. D., DeVincent, C. J., Houts, C. and Edwards, M. C. (2009), Deconstructing the PDD clinical phenotype: internal validity of the DSM-IV. Journal of Child Psychology and Psychiatry, 50: 1246–1254. doi: 10.1111/j.1469-7610.2009.02104.x
- Issue published online: 17 SEP 2009
- Article first published online: 29 JUN 2009
- Manuscript accepted 9 March 2009
- pervasive developmental disorder;
- psychiatric disorder;
- factor analysis
Background: Empirical studies of the structure of autism symptoms have challenged the three-domain model of impairment currently characterizing pervasive developmental disorders (PDD). The objective of this study was to assess the internal validity of the DSM as a conceptual model for describing PDD, while paying particular attention to certain subject characteristics.
Methods: Parents and teachers completed a DSM-IV-referenced rating scale for 3- to 12-year-old clinic referrals with a PDD (n = 730). Ratings were submitted to confirmatory factor analysis and different models were assessed for fit.
Results: Measures of fit indicated that the three-factor solution based on the DSM was superior to other models. Most indices of fit were acceptable, but showed room for improvement. Fit indices varied according to the rater (parent or teacher), child’s age (preschool versus school aged), PDD subtype (autism, Asperger’s, pervasive developmental disorder not otherwise specified (PDDNOS)), and IQ.
Conclusions: More research needs to be done before discarding current classification systems. Subject characteristics, modality of assessment, and procedural variations in statistical analyses impact conclusions about the structure of PDD symptoms.