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Blockade of synaptic inhibition within the pre-Bötzinger complex in the cat suppresses respiratory rhythm generation in vivo
Article first published online: 22 SEP 2004
DOI: 10.1111/j.1469-7793.1998.245bo.x
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How to Cite
Pierrefiche, O., Schwarzacher, S. W., Bischoff, A. M. and Richter, D. W. (1998), Blockade of synaptic inhibition within the pre-Bötzinger complex in the cat suppresses respiratory rhythm generation in vivo. The Journal of Physiology, 509: 245–254. doi: 10.1111/j.1469-7793.1998.245bo.x
Publication History
- Issue published online: 22 SEP 2004
- Article first published online: 22 SEP 2004
- (Received 9 December 1997; accepted after revision 5 February 1998
- , , , & (1991). Inhibition of caudal medullary expiratory neurones by retrofacial inspiratory neurones in the cat. The Journal of Physiology 437, 1–25.
- & (1986). The non-uniform character of expiratory synaptic activity in expiratory bulbospinal neurones in the cat. The Journal of Physiology 370, 433–456.
- , & (1992). Pre-Boetzinger complex in cats: respiratory neuronal discharge patterns. Brain Research 390, 337–340.
- & (1994). Origins of excitatory drive within the respiratory network: anatomical localization. NeuroReport 5, 1933–1936.
- (1986). Brain stem mechanisms for generation and control of breathing pattern. In Handbook of Physiology, section 3, The Respiratory System, vol. II, Control of Breathing, ed. Cherniack, N. S. & , chap. 1, pp. 1–67. American Physiological Society, Bethesda , MD , USA .
- & (1989). Cellular mechanisms underlying modulation of breathing pattern in mammals. Annals of the New York Academy of Sciences 563, 114–130.
- , , , , , , & (1990). Neurogenesis of respiratory rhythm and pattern: emerging concepts. American Journal of Physiology 259, R879–886.
- , , & (1992). Synaptic interaction between medullary respiratory neurones during apneusis induced by NMDA-receptor blockade in cat. The Journal of Physiology 450, 303–323.
- , , (1987). Effects of rostral pontine stimulation on membrane potential of expiratory medullary neurones. Society of Neuroscience Abstracts 13, 1587.
- , & (1989). Involvement of N-methyl-D-aspartate (NMDA) receptors in respiratory rhythmogenesis. Brain Research 500, 199–208.DOI: 10.1016/0006-8993(89)90314-4
- , & (1992). Evidence that glycine and GABA mediate postsynaptic inhibition of bulbar respiratory neurons in the cat. Journal of Applied Physiology 73, 2333–2342.
- & (1992). The role of inhibitory amino acids in control of respiratory motor output in an arterially perfused rat. Respiratory Physiology 89, 47–63.DOI: 10.1016/0034-5687(92)90070-D
- , & (1997). Rostral ventrolateral medulla and respiratory rhythmogenesis in mice. Neuroscience Letters 224, 13–16.DOI: 10.1016/S0304-3940(97)13458-9
- , , & (1994). Pacemaker behavior of respiratory neurons in medullary slices from neonatal rat. Journal of Neurophysiology 72, 2598–2608.
- , & (1993). Late expiratory inhibition of stage 2 expiratory neurons in the cat - a correlate of expiratory termination. Journal of Neurophysiology 70, 1307–1315.
- & (1996). Tonic sympathetic chemoreflex after blockade of respiratory rhythmogenesis in the rat. The Journal of Physiology 491, 859–869.
- , & (1994a). 5-HT-1A receptor-mediated modulation of medullary expiratory neurones in the cat. The Journal of Physiology 476, 117–130.
- , & (1994b). Serotonin 1A-receptor activation suppresses respiratory apneusis. Neuroscience Letters 172, 59–62.DOI: 10.1016/0304-3940(94)90662-9
- (1923). Observations on the respiratory centers in the cat. The Journal of Physiology 57, 153–160.
- , , , & (1992). A network model of respiratory rhythmogenesis. American Journal of Physiology 263, R962–975.
- , & (1988). Primary respiratory rhythm generator in the medulla of brainstem-spinal cord preparation from newborn rat. Brain Research 445, 314–324.DOI: 10.1016/0006-8993(88)91194-8
- , & (1989). Firing properties of respiratory rhythm generating neurons in the absence of synaptic transmission in rat medulla in vitro. Experimental Brain Research 76, 530–536.
- , & (1990). Inhibitory synaptic inputs to the respiratory rhythm generator in the medulla isolated from newborn rats. Pflügers Archiv 417, 425–432.
- , & (1994). Mechanisms of respiratory rhythm generation change profoundly during early life in mice and rats. Neuroscience Letters 170, 167–170.
- & (1995). Role of fast inhibitory synaptic mechanisms in respiratory rhythm generation in the maturing mouse. The Journal of Physiology 484, 505–521.
- , & (1996). Postnatal changes in the mammalian respiratory network as revealed by the transverse brainstem slice of mice. The Journal of Physiology 491, 799–812.
- & (1996). The neuronal mechanisms of respiratory rhythm generation. Current Opinion in Neurobiology 6, 817–825.
- , , , & (1998). Selective lesioning of the cat pre-Bötzinger complex in vivo eliminates breathing but not gasping. The Journal of Physiology 507, 895–907.
- , , , & (1986). Reflex prolongation of stage I of expiration. Pflügers Archiv 407, 190–198.
- (1982). Generation and maintenance of the respiratory rhythm. Journal of Experimental Biology 100, 93–107.
- , & (1992). Mechanisms of respiratory rhythm generation. Current Opinion in Neurobiology 281, 788–793.
- , , & (1979). Studies on the synaptic interconnection between bulbar respiratory neurones of cats. Pflügers Archiv 380, 245–257.
- , , & (1993). Calcium currents and calcium-dependent potassium currents in mammalian medullary respiratory neurones. The Journal of Physiology 470, 23–33.
- , & (1997). Modeling neural mechanisms for genesis of respiratory rhythm and pattern II. Network models of the central respiratory pattern generator. Journal of Neurophysiology 77, 2007–2026.
- , & (1991). Glycine-receptor mediated fast synpatic inhibition in the brainstem respiratory system. Respiratory Physiology 84, 351–361.
- , & (1996). Inhibitions mediated by glycine and GABAA receptors shape the discharge pattern of bulbar respiratory neurons. Brain Research 710, 150–160.
- , & (1995). Pre-Boetzinger complex in the cat. Journal of Neurophysiology 73, 1452–1461.
- , , , & (1991). Pre-Boetzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science 254, 726–729.
- , & (1994). Effects of bicuculline on inspiratory activities in piglets. Brain Research 650, 166–169.
- , , , , , & (1997). Treatment of apneustic respiratory disturbance with a serotonin-receptor agonist. Journal of Pediatrics 130, 89–94.

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